Tyrosine kinase inhibition: an approach to drug development.
about
Substrate recognition by the Lyn protein-tyrosine kinase. NMR structure of the immunoreceptor tyrosine-based activation motif signaling region of the B cell antigen receptorInteraction between protein tyrosine phosphatase and protein tyrosine kinase is involved in androgen-promoted growth of human prostate cancer cellsInhibition of SRC tyrosine kinases suppresses activation of nuclear factor-kappa B, and serine and tyrosine phosphorylation of Ikappa B-alpha in lipopolysaccharide-stimulated RAW 264.7 macrophagesDesign, synthesis and characterization of peptidomimetic conjugate of BODIPY targeting HER2 protein extracellular domainEndosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptorActivation of ErbB2 by 2-methyl-1,4-naphthoquinone (menadione) in human keratinocytes: role of EGFR and protein tyrosine phosphatasesEpidermal growth factor receptor ligands as new extracellular targets for the metastasis-promoting S100A4 proteinRequirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cellsA role for SNX5 in the regulation of macropinocytosisThe m3 muscarinic acetylcholine receptor is coupled to mitogen-activated protein kinase via protein kinase C and epidermal growth factor receptor kinaseCerulein pancreatitis: oxidative stress, inflammation, and apoptosisPlexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and diseaseFrom HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cellsUse of mRNA- and protein-destabilizing elements to develop a highly responsive reporter systemOxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2Mitochondrial Stat3, the Need for Design ThinkingMechanosensory organ regeneration in zebrafish depends on a population of multipotent progenitor cells kept latent by Schwann cells.Structure of Escherichia coli tyrosine kinase Etk reveals a novel activation mechanismMolecular recognition at the active site of catechol-O-methyltransferase (COMT): adenine replacements in bisubstrate inhibitorsMetastasis-associated PRL-3 induces EGFR activation and addiction in cancer cellsStimulation of the mitogen-activated protein kinase cascade and tyrosine phosphorylation of the epidermal growth factor receptor by hepatopoietinThe protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signalingPlatelet-derived growth factor requires epidermal growth factor receptor to activate p21-activated kinase family kinasesA CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinaseLapatinib in the treatment of breast cancerFancy meeting you here! A fresh look at "prokaryotic" protein phosphorylationOleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40Contractile actions of proteinase-activated receptor-derived polypeptides in guinea-pig gastric and lung parenchymal strips: evidence for distinct receptor systemsTyrosine kinase involvement in renal arteriolar constrictor responses to angiotensin IIThrombin-induced p38 mitogen-activated protein kinase activation is mediated by epidermal growth factor receptor transactivation pathwayTumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc.Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitorDietary compound isoliquiritigenin inhibits breast cancer neoangiogenesis via VEGF/VEGFR-2 signaling pathwayCloning and characterisation of Schistosoma japonicum insulin receptorsDefects in ErbB-dependent establishment of adult melanocyte stem cells reveal independent origins for embryonic and regeneration melanocytesThe Frog Skin-Derived Antimicrobial Peptide Esculentin-1a(1-21)NH2 Promotes the Migration of Human HaCaT Keratinocytes in an EGF Receptor-Dependent Manner: A Novel Promoter of Human Skin Wound Healing?The emergence of ErbB2 expression in cultured rat hepatocytes correlates with enhanced and diversified EGF-mediated signalingFormation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors
P2860
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P2860
Tyrosine kinase inhibition: an approach to drug development.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Tyrosine kinase inhibition: an approach to drug development.
@en
type
label
Tyrosine kinase inhibition: an approach to drug development.
@en
prefLabel
Tyrosine kinase inhibition: an approach to drug development.
@en
P356
P1433
P1476
Tyrosine kinase inhibition: an approach to drug development.
@en
P2093
P304
P356
10.1126/SCIENCE.7892601
P407
P577
1995-03-01T00:00:00Z