Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine.
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Role of ROS and RNS Sources in Physiological and Pathological ConditionsThe autophagy-lysosomal system in subarachnoid haemorrhageThe Potential Role of the Proteases Cathepsin D and Cathepsin L in the Progression and Metastasis of Epithelial Ovarian CancerUsing the social amoeba Dictyostelium to study the functions of proteins linked to neuronal ceroid lipofuscinosisInteractions of the proteins of neuronal ceroid lipofuscinosis: clues to functionBid regulates the pathogenesis of neurotropic reovirus.Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domainHepatocyte death: a clear and present danger.Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.Attenuation of the lysosomal death pathway by lysosomal cholesterol accumulation.Long-term quiescent fibroblast cells transit into senescenceThe propeptide of yeast cathepsin D inhibits programmed necrosis.Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.Wilms' tumor gene 1 (WT1) silencing inhibits proliferation of malignant peripheral nerve sheath tumor sNF96.2 cell line.Calcium-independent phospholipase A2 localizes in and protects mitochondria during apoptotic induction by staurosporine.Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochrome c.Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brainApoptosis in cerebral ischemia: executional and regulatory signaling mechanisms.Commitment to apoptosis in CD4(+) T lymphocytes productively infected with human immunodeficiency virus type 1 is initiated by lysosomal membrane permeabilization, itself induced by the isolated expression of the viral protein NefAlteration of cathepsin-D expression in atrophied muscles and apoptotic myofibers by hindlimb unloading in a low-temperature environment.Overexpression of both catalytically active and -inactive cathepsin D by cancer cells enhances apoptosis-dependent chemo-sensitivityCaspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation.Lysosome-targeted stress reveals increased stability of lipofuscin-containing lysosomes.Geranylated 4-Phenylcoumarins Exhibit Anticancer Effects against Human Prostate Cancer Cells through Caspase-Independent Mechanism.Protease signalling in cell death: caspases versus cysteine cathepsins.Lysosomal cysteine cathepsins: signaling pathways in apoptosis.Yes-associated protein (YAP) promotes cell survival by inhibiting proapoptotic dendrin signalingCathepsin D overexpressed by cancer cells can enhance apoptosis-dependent chemo-sensitivity independently of its catalytic activity.Apoptosis and necrosis of human breast cancer cells by an aqueous extract of garden cress (Lepidium sativum) seedsAcetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D releaseConserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence.Calcium overload is essential for the acceleration of staurosporine-induced cell death following neuronal differentiation in PC12 cellsApolipoprotein E4 Elicits Lysosomal Cathepsin D Release, Decreased Thioredoxin-1 Levels, and Apoptosis.Natural Products Diversity of Marine Ascidians (Tunicates; Ascidiacea) and Successful Drugs in Clinical Development.Vacuole-mitochondrial cross-talk during apoptosis in yeast: a model for understanding lysosome-mitochondria-mediated apoptosis in mammals.Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL.Inherited diseases caused by mutations in cathepsin protease genes.Yeast as a tool to explore cathepsin D function.MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosisHypersensitivity of mtDNA-depleted cells to staurosporine-induced apoptosis: roles of Bcl-2 downregulation and cathepsin B.
P2860
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P2860
Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Cathepsin D mediates cytochrom ...... osis induced by staurosporine.
@en
type
label
Cathepsin D mediates cytochrom ...... osis induced by staurosporine.
@en
prefLabel
Cathepsin D mediates cytochrom ...... osis induced by staurosporine.
@en
P2093
P356
P1476
Cathepsin D mediates cytochrom ...... osis induced by staurosporine.
@en
P2093
P2888
P304
P356
10.1038/SJ.CDD.4401290
P577
2003-11-01T00:00:00Z
P5875
P6179
1052920101