B-raf, a new member of the raf family, is activated by DNA rearrangement.
about
B-Raf and the inhibitors: from bench to bedsidevav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cellsDifferential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanismsCloning and characterization of the cDNA coding for a polymyositis-scleroderma overlap syndrome-related nucleolar 100-kD proteinAutoregulation of the Raf-1 serine/threonine kinaseBRAF Mutation in Colorectal Cancer: An UpdateMutation of the BRAF genes in non-small cell lung cancerTargeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyondOncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer.B-raf oncogene: activation by rearrangements and assignment to human chromosome 7RASSF1A and NORE1A methylation and BRAFV600E mutations in thyroid tumorsB-raf alternative splicing is dispensable for development but required for learning and memory associated with the hippocampus in the adult mouseForebrain-specific knockout of B-raf kinase leads to deficits in hippocampal long-term potentiation, learning, and memoryHepatic epidermal growth factor-regulated mitogen-activated protein kinase kinase kinase activity in the rat: lack of identity with known forms of raf and MEKKConditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cellsBiochemical Analysis of MEK Activation in NIH3T3 FibroblastsMutational activation of c-raf-1 and definition of the minimal transforming sequence.Inhibition of platelet-derived growth factor- and epidermal growth factor-mediated mitogenesis and signaling in 3T3 cells expressing delta Raf-1:ER, an estradiol-regulated form of Raf-1.Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase.Raf-1 N-terminal sequences necessary for Ras-Raf interaction and signal transduction.Molecular organization of the human Raf-1 promoter region.Development of a highly efficient expression cDNA cloning system: application to oncogene isolation.Parthenolide suppresses non-small cell lung cancer GLC-82 cells growth via B-Raf/MAPK/Erk pathwayA genetic linkage map of mouse chromosome 10: localization of eighteen molecular markers using a single interspecific backcrossA brief history of melanoma: from mummies to mutationsUnique N-region determines low basal activity and limited inducibility of A-RAF kinase: the role of N-region in the evolutionary divergence of RAF kinase function in vertebrates.A novel oncogene related to c-mil is transduced in chicken neuroretina cells induced to proliferate by infection with an avian lymphomatosis virusDetection of BRAF(V600E) Mutations in Papillary Thyroid Carcinomas by Peptide Nucleic Acid Clamp Real-Time PCR: A Comparison with Direct SequencingRaf kinases: oncogenesis and drug discovery.Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1.Occurrence of alternatively spliced leader-delta onc-poly(A) transcripts in chicken neuroretina cells infected with Rous-associated virus type 1: implication in transduction of the c-mil/c-raf and c-Rmil/B-raf oncogenesThe mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression.Epidermal growth factor (EGF) stimulates association and kinase activity of Raf-1 with the EGF receptor.95-kilodalton B-Raf serine/threonine kinase: identification of the protein and its major autophosphorylation site.Common mechanism of retrovirus activation and transduction of c-mil and c-Rmil in chicken neuroretina cells infected with Rous-associated virus type 1.Induction of transformation and DNA synthesis after microinjection of raf proteinsDefinition of the human raf amino-terminal regulatory region by deletion mutagenesis.Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase.BRAF(E600) in benign and malignant human tumours.Mechanistic principles of RAF kinase signaling.
P2860
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P2860
B-raf, a new member of the raf family, is activated by DNA rearrangement.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
B-raf, a new member of the raf family, is activated by DNA rearrangement.
@en
type
label
B-raf, a new member of the raf family, is activated by DNA rearrangement.
@en
prefLabel
B-raf, a new member of the raf family, is activated by DNA rearrangement.
@en
P2093
P2860
P356
P1476
B-raf, a new member of the raf family, is activated by DNA rearrangement.
@en
P2093
P2860
P304
P356
10.1128/MCB.8.6.2651
P407
P577
1988-06-01T00:00:00Z