Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways. - Wikidata - wikimedia - TriplyDB

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways.

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways.

http://www.wikidata.org/entity/Q40666435

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Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance Regulation of Bim in Health and Disease FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos Hypoxia-induced modulation of apoptosis and BCL-2 family proteins in different cancer cell types N-cadherin mediates neuronal cell survival through Bim down-regulation.Sodium tanshinone IIA sulfonate protects rat myocardium against ischemia-reperfusion injury via activation of PI3K/Akt/FOXO3A/Bim pathway.Activity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypes Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim.The Erk2 MAPK regulates CD8 T cell proliferation and survival.G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression.Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes.Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.SDPR functions as a metastasis suppressor in breast cancer by promoting apoptosis.Raf-1 activation prevents caspase 9 processing downstream of apoptosome formation.Bim protein degradation contributes to cisplatin resistance.Treatment of a human papillomavirus type 31b-positive cell line with benzo[a]pyrene increases viral titer through activation of the Erk1/2 signaling pathway A critical role for TNF receptor-associated factor 1 and Bim down-regulation in CD8 memory T cell survival.Transforming growth factor beta (TGFbeta)-induced apoptosis: the rise & fall of Bim Radiotherapy-induced plasticity of prostate cancer mobilizes stem-like non-adherent, Erk signaling-dependent cells p38α Signaling Induces Anoikis and Lumen Formation During Mammary Morphogenesis.Men are but worms: neuronal cell death in C elegans and vertebrates.Tadalafil, a Phosphodiesterase Inhibitor Protects Stem Cells over Longer Period Against Hypoxia/Reoxygenation Injury Through STAT3/PKG-I Signaling.Bim is required for T-cell allogeneic responses and graft-versus-host disease in vivo.MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism NO mobilizes intracellular Zn2+ via cGMP/PKG signaling pathway and prevents mitochondrial oxidant damage in cardiomyocytes.Allopurinol Protects against Ischemia/Reperfusion-Induced Injury in Rat Urinary Bladders The major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes.Expression of RKIP, E-cadherin and NF-kB p65 in esophageal squamous cell carcinoma and their correlations.BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway.BCL2 family of apoptosis-related genes: functions and clinical implications in cancer.Crosstalk between Bcl-2 family and Ras family small GTPases: potential cell fate regulation?Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering.Organ transplantation in rodents: novel applications of long-established methods.Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy.Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.Leptin protects hippocampal CA1 neurons against ischemic injury.The BH3-only protein Bim plays a critical role in leukemia cell death triggered by concomitant inhibition of the PI3K/Akt and MEK/ERK1/2 pathways.

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Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways.

http://www.wikidata.org/entity/Q40666435

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2003年论文

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2003年论文

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name

Activation of ERK1/2 by deltaR ...... y of the JNK or PI3K pathways.

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type

label

Activation of ERK1/2 by deltaR ...... y of the JNK or PI3K pathways.

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prefLabel

Activation of ERK1/2 by deltaR ...... y of the JNK or PI3K pathways.

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Claire Chalmers

http://www.w3.org/2001/XMLSchema#string

Claire R Weston

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Kathryn Balmanno

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Kathryn Hadfield

http://www.w3.org/2001/XMLSchema#string

Rebecca Ley

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Sarah A Molton

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Simon J Cook

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P2860

The cell death-promoting gene DP5, which interacts with the BCL2 family, is induced during neuronal apoptosis following exposure to amyloid beta protein

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

Breaking the mitochondrial barrier.

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins.

Ras signalling and apoptosis.

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation.

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

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22

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12618753

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