Glucose metabolism in cancer. Evidence that demethylation events play a role in activating type II hexokinase gene expression.
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The metabolic advantage of tumor cellsHexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondriaEnvironmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genomeHexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapyConserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarraysRestoration of mitochondria function as a target for cancer therapyTumor suppressor p53 and its mutants in cancer metabolismRole of epigenetic aberrations in the development and progression of human hepatocellular carcinomaHexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibitionMethylated DNA binding domain protein 2 (MBD2) coordinately silences gene expression through activation of the microRNA hsa-mir-496 promoter in breast cancer cell lineEvidence for heightened hexokinase II immunoexpression in hepatocyte dysplasia and hepatocellular carcinomaTRIM24 links glucose metabolism with transformation of human mammary epithelial cellsEnergetics, epigenetics, mitochondrial genetics.The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase.Causes and consequences of DNA hypomethylation in human cancer.Mitochondria and cancer: Warburg addressed.delta-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profilesTargeting the metabolic microenvironment of tumors.Mitochondrial and nuclear genes of mitochondrial components in cancer.Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics.A causal link from ALK to hexokinase II overexpression and hyperactive glycolysis in EML4-ALK-positive lung cancerRegulation of HK2 expression through alterations in CpG methylation of the HK2 promoter during progression of hepatocellular carcinoma.Regulation of glycolysis in head and neck squamous cell carcinoma.Epigenetics and cancer metabolism.The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies.Proteomics revisits the cancer metabolome.Mitochondrial metabolism inhibitors for cancer therapy.Interactions between epigenetics and metabolism in cancers.Hepatitis B virus X protein-induced aberrant epigenetic modifications contributing to human hepatocellular carcinoma pathogenesis.The Warburg effect: molecular aspects and therapeutic possibilities.Metabostemness: a new cancer hallmark.Non-metabolic functions of glycolytic enzymes in tumorigenesis.miR-143 regulates hexokinase 2 expression in cancer cells.c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinomaInduction of the human heat shock promoter HSP70B by nutritional stress: implications for cancer gene therapy.Functional analysis of Drosophila melanogaster hexokinase Hex-A locus: multiple Initiator-like elements enhance DPE containing promoter activity.Valproate induces replication-independent active DNA demethylation.Can metabolic plasticity be a cause for cancer? Warburg-Waddington legacy revisited.Regeneration and DNA demethylation do not trigger PDX-1 expression in rat hepatocytes.Epigenetic programming of the rRNA promoter by MBD3.
P2860
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P2860
Glucose metabolism in cancer. Evidence that demethylation events play a role in activating type II hexokinase gene expression.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Glucose metabolism in cancer. ...... II hexokinase gene expression.
@en
type
label
Glucose metabolism in cancer. ...... II hexokinase gene expression.
@en
prefLabel
Glucose metabolism in cancer. ...... II hexokinase gene expression.
@en
P2093
P2860
P356
P1476
Glucose metabolism in cancer. ...... II hexokinase gene expression.
@en
P2093
Ashish Goel
Peter L Pedersen
Saroj P Mathupala
P2860
P304
15333-15340
P356
10.1074/JBC.M300608200
P407
P577
2003-02-03T00:00:00Z