Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing.
about
Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosisTrailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer CellsCell biology. Metabolic control of cell deathEfficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapyTRAIL-mediated apoptosis in breast cancer cells cultured as 3D spheroidsIdentification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening.Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies.Utilization of the cellular stress response to sensitize cancer cells to TRAIL-mediated apoptosis.Tipping the balance in the powerhouse of the cell to "protect" colorectal cancer.The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracilExpression of SGLT1, Bcl-2 and p53 in primary pancreatic cancer related to survival.Glucose deprivation triggers protein kinase C-dependent β-catenin proteasomal degradation.Cancer metabolism: current perspectives and future directions.Metabolic stress in autophagy and cell death pathwaysGSK-3β signaling determines autophagy activation in the breast tumor cell line MCF7 and inclusion formation in the non-tumor cell line MCF10A in response to proteasome inhibition.Hyperglycemic Conditions Prime Cells for RIP1-dependent Necroptosis.Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene.Targeting the metabolic pathway of human colon cancer overcomes resistance to TRAIL-induced apoptosis.Sugar-free approaches to cancer cell killing.Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors.Switching from aerobic glycolysis to oxidative phosphorylation modulates the sensitivity of mantle cell lymphoma cells to TRAIL.Inhibition of cellular FLICE-like inhibitory protein abolishes insensitivity to interferon-α and death receptor stimulation in resistant variants of the human U937 cell line.Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression.Mitotic arrest and JNK-induced proteasomal degradation of FLIP and Mcl-1 are key events in the sensitization of breast tumor cells to TRAIL by antimicrotubule agents.Therapeutic starvation and autophagy in prostate cancer: a new paradigm for targeting metabolism in cancer therapyRoscovitine sensitizes breast cancer cells to TRAIL-induced apoptosis through a pleiotropic mechanism.Possible mechanism for the regulation of glucose on proliferation, inhibition and apoptosis of colon cancer cells induced by sodium butyrate.Interference with energy metabolism by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside induces HPV suppression in cervical carcinoma cells and apoptosis in the absence of LKB1.Identification of transcriptional targets associated with the expression of p210 Bcr-Abl.Thymidylate synthase inhibition triggers glucose-dependent apoptosis in p53-negative leukemic cells.Down-regulation of Sp1 activity through modulation of O-glycosylation by treatment with a low glucose mimetic, 2-deoxyglucose.Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.Can radiation-induced apoptosis be modulated by inhibitors of energy metabolism?The changing dielectric properties of CHO cells can be used to determine early apoptotic events in a bioprocess.Regulation of TNF-Related Apoptosis-Inducing Ligand Signaling by Glycosylation.
P2860
Q24338378-F76A208A-1D26-4CF3-AA93-6AD624EF76C8Q28391040-55728ACE-E229-409F-B8EC-DF66527A5C89Q28397089-F3F14AE1-9C27-4478-8C93-E111FAFF4006Q28477131-3C5AC911-63EE-419B-8DCB-0C38492226D5Q28544399-4576E8D5-B56A-4521-ADEF-2E6967381B36Q33739941-52371B81-3A76-47D2-B690-D15957973906Q34081705-84B13EC5-E376-4B70-858D-2A19A041DDA9Q34286028-4AF38C5C-F2DC-437C-BD88-52BD1887D97DQ34299435-0DEDF7E5-ECCB-46CB-B9EF-86031E5A75C5Q34607831-F63CEF0B-D50D-44CE-9245-57721DB058E7Q34657372-14A1E7A4-70F9-4D37-83BC-5443ABF1DEA3Q35352122-F3E7E730-2BCC-417A-B402-4EAE9D602A8DQ35723836-6CBAE370-6042-4F89-B9D5-46D17E314962Q36192905-C25200E2-B9DB-4412-A466-7A3277C34A31Q36890223-9058AA37-0830-4E36-90E5-665F69406675Q37034432-F71822E7-50FD-46A6-AACA-884614E4C9A1Q37038401-1DB6D792-A05A-4A36-8D55-850F0DD79688Q37246966-BC1FBE50-9522-49FF-BE54-616545621926Q37802748-40D05368-B319-4386-ACFC-85488CD6A47AQ38938720-502ACF6A-7EC0-496C-8604-570DB91E16EAQ39400792-A0E39BF2-40B0-4AA5-943E-9CBB2395DBDCQ39544475-2A12168D-505E-43C9-B46E-F1F3FB3A4C9CQ39761800-EDEC2DFB-C265-4108-B660-01F5AF7D58C5Q39770080-97B37C56-769A-43EA-AD0C-A75D6F4F404EQ39944174-B4CCB1C3-DFD3-4B02-A1CE-0951CCC1BC93Q39985088-7BF1AB1F-CF35-4202-BD88-E8B475B28C06Q40100631-66619F6F-4103-4F80-90B7-AA20DB754073Q40185102-B15B5874-18AC-4D1E-9116-0EA4352698D2Q40312982-6152D6A5-5309-4600-85C6-0397E43614FEQ40536258-0191B103-27BA-4366-8201-89ECBAD428E1Q40628182-22E628FC-A138-4AAC-BA44-99765999669BQ43228472-C380A582-2D94-4618-AE8A-6E9BF675B6BDQ46955859-76CA86BB-1B4E-486C-9118-139C63377BD0Q50231756-D4FEFB29-9017-4AF3-B8DC-C85A0A8528E2Q52369544-BEB1855F-216E-4326-BE45-05A9F3953C68
P2860
Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Inhibition of glucose metaboli ...... pical procaspase-8 processing.
@en
type
label
Inhibition of glucose metaboli ...... pical procaspase-8 processing.
@en
prefLabel
Inhibition of glucose metaboli ...... pical procaspase-8 processing.
@en
P2860
P50
P356
P1476
Inhibition of glucose metaboli ...... pical procaspase-8 processing.
@en
P2093
Carmen Ruiz de Almodóvar
Carmen Ruiz-Ruiz
P2860
P304
12759-12768
P356
10.1074/JBC.M212392200
P407
P577
2003-01-29T00:00:00Z