Enhanced activation of mitogen-activated protein kinase and myosin light chain kinase by the Pro33 polymorphism of integrin beta 3.
about
HPA-1 polymorphism of alphaIIbbeta3 modulates platelet adhesion onto immobilized fibrinogen in an in-vitro flow system.Pro32Pro33 mutations in the integrin β3 PSI domain result in αIIbβ3 priming and enhanced adhesion: reversal of the hypercoagulability phenotype by the Src inhibitor SKI-606.Polymorphism in Integrin ITGA2 is Associated with Ischemic Stroke and Altered Serum Cholesterol in Chinese Individuals.Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen.The Leu33Pro polymorphism in the ITGB3 gene does not modify BRCA1/2-associated breast or ovarian cancer risks: results from a multicenter study among 15,542 BRCA1 and BRCA2 mutation carriers.Genetics of platelet glycoprotein receptors: risk of thrombotic events and pharmacogenetic implications.Effect of PlA1/A2 glycoprotein IIIa gene polymorphism on the long-term outcome after successful coronary stenting.Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma.Molecular mechanisms of prothrombotic risk due to genetic variations in platelet genes: Enhanced outside-in signaling through the Pro33 variant of integrin beta3.No association of breast cancer risk with integrin beta3 (ITGB3) Leu33Pro genotype.Beta3 integrin haplotype influences gene regulation and plasma von Willebrand factor activityImpact of platelet phenotype on myocardial infarction.Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling.Integrin beta3 Leu33Pro polymorphism increases BRCA1-associated ovarian cancer risk.Protein phosphatase 1 associates with the integrin alphaIIb subunit and regulates signaling.The Pro33 isoform of integrin beta3 enhances outside-in signaling in human platelets by regulating the activation of serine/threonine phosphatases.CHO cells expressing the high affinity alpha(IIb)beta3 T562N integrin demonstrate enhanced adhesion under shear.The Gain-of-Function Integrin β3 Pro33 Variant Alters the Serotonin System in the Mouse Brain.A1/A2 polymorphism of the glycoprotein IIIa gene and diabetic retinopathy in Caucasians with type 2 diabetes.Functional polymorphism rs710218 in the gene coding GLUT1 protein is associated with in-stent restenosis.Platelet glycoprotein IIIA PIA1/A2 polymorphism in young patients with ST elevation myocardial infarction and idiopathic ischemic stroke.
P2860
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P2860
Enhanced activation of mitogen-activated protein kinase and myosin light chain kinase by the Pro33 polymorphism of integrin beta 3.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Enhanced activation of mitogen ...... lymorphism of integrin beta 3.
@en
type
label
Enhanced activation of mitogen ...... lymorphism of integrin beta 3.
@en
prefLabel
Enhanced activation of mitogen ...... lymorphism of integrin beta 3.
@en
P2093
P2860
P356
P1476
Enhanced activation of mitogen ...... lymorphism of integrin beta 3.
@en
P2093
Jing-Fei Dong
K Vinod Vijayan
Paul F Bray
P2860
P304
P356
10.1074/JBC.M208680200
P407
P577
2002-11-29T00:00:00Z