Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.
about
pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epitheliaMolecular epidemiological study of non-small-cell lung cancer from an environmentally polluted region of PolandRibosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulatorEnhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells.Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle controlWidely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesisTrans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesisMechanisms of resistance to alkylating agentsMolecular biology of lung cancer: clinical implicationsRepression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosisRapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe arrayAcrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repairAristolochic acid and the etiology of endemic (Balkan) nephropathyLung cancer. 1: prevention of lung cancerGenes other than BRCA1 and BRCA2 involved in breast cancer susceptibilityLow density DNA microarray for detection of most frequent TP53 missense point mutationsDNA microarrays on a dendron-modified surface improve significantly the detection of single nucleotide variations in the p53 genePreponderance of the oncogenic V599E and V599K mutations in B-raf kinase domain is enhanced in melanoma cutaneous/subcutaneous metastasesThe role of transgenic mouse models in carcinogen identificationImmunologic aspect of ovarian cancer and p53 as tumor antigen.Mechanisms of drug resistance in colon cancer and its therapeutic strategiesOncogenic Intra-p53 Family Member Interactions in Human CancersPolycyclic Aromatic Hydrocarbons and Breast Cancer: A Review of the LiteratureMutational signatures: the patterns of somatic mutations hidden in cancer genomesChemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promisingTargeting the Bcl-2 family for cancer therapyEfficient Atomistic Simulation of Pathways and Calculation of Rate Constants for a Protein-Peptide Binding Process: Application to the MDM2 Protein and an Intrinsically Disordered p53 Peptide.The Tumor Suppressor BCL7B Functions in the Wnt Signaling PathwayStructural Perturbations Induced by the α-Anomer of the Aflatoxin B 1 Formamidopyrimidine Adduct in Duplex and Single-Strand DNAStructure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding ProteinBypass of Aflatoxin B 1 Adducts by the Sulfolobus solfataricus DNA Polymerase IVMutations in residues of TP53 that directly contact DNA predict poor outcome in human primary breast cancer.Pathophysiological Role of Peroxynitrite Induced DNA Damage in Human Diseases: A Special Focus on Poly(ADP-ribose) Polymerase (PARP)Somatic mutation analysis of p53 and ST7 tumor suppressor genes in gastric carcinoma by DHPLCGlutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinomaIncreased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseasesMethylation mattersTranscriptional dysregulation of the p73L / p63 / p51 / p40 / KET gene in human squamous cell carcinomas: expression of Delta Np73L, a novel dominant-negative isoform, and loss of expression of the potential tumour suppressor p51Alterations in the K-ras and p53 genes in rat lung tumorsp53 polymorphisms associated with mutations in and loss of heterozygosity of the p53 gene in male oral squamous cell carcinomas in Taiwan
P2860
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P2860
Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Mutations in the p53 tumor sup ...... gy and molecular pathogenesis.
@en
type
label
Mutations in the p53 tumor sup ...... gy and molecular pathogenesis.
@en
prefLabel
Mutations in the p53 tumor sup ...... gy and molecular pathogenesis.
@en
P2093
P1433
P1476
Mutations in the p53 tumor sup ...... gy and molecular pathogenesis.
@en
P2093
Bennett WP
Greenblatt MS
Hollstein M
P304
P407
P577
1994-09-01T00:00:00Z