Structure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding Protein
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Fuzzy complexes: Specific binding without complete foldingFine-tuning multiprotein complexes using small moleculesWrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulatorsAtomic Structure of Dual-Specificity Phosphatase 26, a Novel p53 PhosphataseConformational Selection and Folding-upon-binding of Intrinsically Disordered Protein CP12 Regulate Photosynthetic Enzymes AssemblyHigh-resolution structure of TBP with TAF1 reveals anchoring patterns in transcriptional regulationThe DNA-binding domain mediates both nuclear and cytosolic functions of p53Nucleosome distortion as a possible mechanism of transcription activation domain functionp53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum ConceptPredicting transcriptional activity of multiple site p53 mutants based on hybrid propertiesModulation of the disordered conformational ensembles of the p53 transactivation domain by cancer-associated mutationsMisfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.Expanding the Range of Protein Function at the Far End of the Order-Structure ContinuumIs a malleable protein necessarily highly dynamic? The hydrophobic core of the nuclear coactivator binding domain is well ordered.Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectivesMembrane-Induced Folding of the Plant Stress Dehydrin Lti30.The transition state structure for coupled binding and folding of disordered protein domains.Emergence and evolution of an interaction between intrinsically disordered proteins.Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseasesTranscriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.Residual structures, conformational fluctuations, and electrostatic interactions in the synergistic folding of two intrinsically disordered proteins.Expanding the proteome: disordered and alternatively folded proteins.Fast association and slow transitions in the interaction between two intrinsically disordered protein domains.Shared structural features of the 9aaTAD family in complex with CBP.The 9aaTAD Is Exclusive Activation Domain in Gal4.Global conformational selection and local induced fit for the recognition between intrinsic disordered p53 and CBPFunctional advantages of dynamic protein disorder.Competitive binding between dynamic p53 transactivation subdomains to human MDM2 protein: implications for regulating the p53·MDM2/MDMX interaction.p53 N-terminal phosphorylation: a defining layer of complex regulationJust a Flexible Linker? The Structural and Dynamic Properties of CBP-ID4 Revealed by NMR Spectroscopy.Dual-site interactions of p53 protein transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways.Role of Intrinsic Protein Disorder in the Function and Interactions of the Transcriptional Coactivators CREB-binding Protein (CBP) and p300Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.Mechanism and rate constants of the Cdc42 GTPase binding with intrinsically disordered effectors.Discovery of Transcriptional Targets Regulated by Nuclear Receptors Using a Probabilistic Graphical ModelStructural investigation on the intrinsically disordered N-terminal region of HPV16 E7 protein.Accurate optimization of amino acid form factors for computing small-angle X-ray scattering intensity of atomistic protein structures.How do dynamic cellular signals travel long distances?Real-time and simultaneous monitoring of the phosphorylation and enhanced interaction of p53 and XPC acidic domains with the TFIIH p62 subunit.ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain.
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P2860
Structure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding Protein
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structure of the p53 Transacti ...... Domain of CREB Binding Protein
@ast
Structure of the p53 Transacti ...... Domain of CREB Binding Protein
@en
Structure of the p53 Transacti ...... Domain of CREB Binding Protein
@nl
type
label
Structure of the p53 Transacti ...... Domain of CREB Binding Protein
@ast
Structure of the p53 Transacti ...... Domain of CREB Binding Protein
@en
Structure of the p53 Transacti ...... Domain of CREB Binding Protein
@nl
prefLabel
Structure of the p53 Transacti ...... Domain of CREB Binding Protein
@ast
Structure of the p53 Transacti ...... Domain of CREB Binding Protein
@en
Structure of the p53 Transacti ...... Domain of CREB Binding Protein
@nl
P2860
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P1433
P1476
Structure of the p53 transacti ...... domain of CREB binding protein
@en
P2093
Chul Won Lee
Maria A Martinez-Yamout
P2860
P304
P3181
P356
10.1021/BI1012996
P407
P577
2010-10-29T00:00:00Z