Mutations of the Yku80 C terminus and Xrs2 FHA domain specifically block yeast nonhomologous end joining
about
Eukaryotic DNA ligases: structural and functional insightsRecruitment of Saccharomyces cerevisiae Dnl4-Lif1 complex to a double-strand break requires interactions with Yku80 and the Xrs2 FHA domainForkhead-associated domain of yeast Xrs2, a homolog of human Nbs1, promotes nonhomologous end joining through interaction with a ligase IV partner protein, Lif1Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signalingYeast Nej1 is a key participant in the initial end binding and final ligation steps of nonhomologous end joining.A novel function for the Mre11-Rad50-Xrs2 complex in base excision repair.Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae.Cyclin-dependent kinase-dependent phosphorylation of Lif1 and Sae2 controls imprecise nonhomologous end joining accompanied by double-strand break resection.Identification of Plasmodium falciparum DNA Repair Protein Mre11 with an Evolutionarily Conserved Nuclease FunctionNonhomologous end joining: a good solution for bad endsRibosomal DNA status inferred from DNA cloud assays and mass spectrometry identification of agarose-squeezed proteins interacting with chromatin (ASPIC-MS).A strategy for interaction site prediction between phospho-binding modules and their partners identified from proteomic dataRegulation of Ku-DNA association by Yku70 C-terminal tail and SUMO modificationRelease of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity.Yeast DNA ligase IV mutations reveal a nonhomologous end joining function of BRCT1 distinct from XRCC4/Lif1 binding.The Rad50 coiled-coil domain is indispensable for Mre11 complex functionsSumoylation influences DNA break repair partly by increasing the solubility of a conserved end resection protein.Electron microscopy visualization of DNA-protein complexes formed by Ku and DNA ligase IVGenome-wide screens for sensitivity to ionizing radiation identify the fission yeast nonhomologous end joining factor Xrc4.The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA-Dependent Tel1 Activation.The cellular response to chromosome breakage.Overhang polarity of chromosomal double-strand breaks impacts kinetics and fidelity of yeast non-homologous end joiningDNA damage responses in Drosophila nbs mutants with reduced or altered NBS function.Role of the yeast DNA repair protein Nej1 in end processing during the repair of DNA double strand breaks by non-homologous end joiningRepair of double-strand breaks by end joining.Cell cycle regulation of homologous recombination in Saccharomyces cerevisiae.RSC facilitates Rad59-dependent homologous recombination between sister chromatids by promoting cohesin loading at DNA double-strand breaks.Consider the workhorse: Nonhomologous end-joining in budding yeast.How do telomeres and NHEJ coexist?Regulation of non-homologous end joining via post-translational modifications of components of the ligation step.HDF1 and RAD17 genes are involved in DNA double-strand break repair in stationary phase Saccharomyces cerevisiae.In Saccharomyces cerevisiae, yKu and subtelomeric core X sequences repress homologous recombination near telomeres as part of the same pathway.The association of yKu with subtelomeric core X sequences prevents recombination involving telomeric sequences.Saccharomyces cerevisiae Mhr1 can bind Xho I-induced mitochondrial DNA double-strand breaks in vivo.Deletion of a KU80 homolog enhances homologous recombination in the thermotolerant yeast Kluyveromyces marxianus.Ku DNA End-Binding Activity Promotes Repair Fidelity and Influences End-Processing During Nonhomologous End-Joining in Saccharomyces cerevisiae.
P2860
Q24617266-F41AE676-3DBD-46B5-A37A-DB65F926F313Q24646357-916B25EA-312E-47B5-B3BB-6966590D3C57Q24652934-DAF31AF5-23CE-464A-9708-0CD6C1B6FF7AQ24682173-A29600B1-672E-442E-8655-EC447AB75518Q27681577-F886599D-E9B0-478D-81E9-6CA5E8A764EBQ27933248-BEF2FB4D-2557-4419-806B-004387E6C09CQ27934572-A42F3BD8-0803-4606-A6D5-7435FA2D1382Q27936134-6E094F57-AC07-4857-BFFE-3EC60AE9C3E9Q27936403-EB19E9AA-C23F-42A9-B243-1457AC01AF98Q30043338-E122AF9B-51CA-41B3-A77E-57F98611CF9AQ33625010-BEEE14D7-3474-49FF-B754-DA801B89869FQ33648731-39246FAD-791C-425B-A452-4731E324F86CQ33669971-50CD4C80-D9DC-49A1-9BD1-08BF8ED0DDBAQ33675631-16DC336E-F053-48BE-A680-6567BB4F4637Q34023042-CD951DD5-4B7A-4698-B1A2-BA41D3EAFED5Q34795549-3E1012B9-2540-41A9-BD37-0CB5C7E3CE99Q35007981-A05C3116-DBB8-4E12-A4BE-A639CBEC197BQ35300475-592D6F15-8667-4C23-BCC4-D46A534CF747Q35539883-40BCEFB2-A883-41C9-B29C-6F283AFC1C05Q35661237-8D35FA06-8D01-43D8-8C48-EBAC3F108173Q35683678-8B11EB76-F93E-4FE4-9040-68C7C996279DQ35962395-43D8BA18-B964-4AD2-B4C7-5425032624B5Q36475466-1E038234-A16E-403B-80EB-94E67A4A1F89Q36775535-72DC2B29-5DB6-4319-BADA-A5E9C33904FEQ37243301-F8CF818D-9B7F-4A7A-8C05-70A99AF70379Q37289660-BFBD8F0A-5099-4D48-97EC-16E2A8E139B8Q38103528-1A312F68-C748-4695-B6BD-A60E054C4204Q38183861-C4DA5B75-A71D-4D67-AD3E-0529C4416649Q38630544-16864BC7-9E29-44E8-8BF6-D0C559A9991AQ38848161-85D786D8-0CCD-4C8A-8F6B-DABCE5AB2A2EQ38866701-1DC15FDF-FD47-4234-8693-251D74F0530BQ39028618-E20AC78B-34F0-49A1-AA17-AEAE211C3513Q41824606-8255A98C-A4F0-4956-B1F8-BB601082BD10Q42590640-BDF64A99-358B-4B2A-9D6D-65E0EB0FD95FQ42590642-B6E4F699-53D8-462B-B50E-4A9023216FDDQ47652155-B25CF534-025A-437F-B92A-0470A87C7CFBQ52651098-A2625B52-82B6-45FC-8EE8-FE06DB0E827AQ52676508-C796C4D2-A4A2-4A3C-B06D-5F753293CD0E
P2860
Mutations of the Yku80 C terminus and Xrs2 FHA domain specifically block yeast nonhomologous end joining
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Mutations of the Yku80 C termi ...... east nonhomologous end joining
@en
type
label
Mutations of the Yku80 C termi ...... east nonhomologous end joining
@en
prefLabel
Mutations of the Yku80 C termi ...... east nonhomologous end joining
@en
P2093
P2860
P1476
Mutations of the Yku80 C termi ...... east nonhomologous end joining
@en
P2093
James M Daley
Phillip L Palmbos
Thomas E Wilson
P2860
P304
10782-10790
P356
10.1128/MCB.25.24.10782-10790.2005
P407
P577
2005-12-01T00:00:00Z