Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex.
about
Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replicationInteraction of the adenovirus type 5 E4 Orf3 protein with promyelocytic leukemia protein isoform II is required for ND10 disruption.The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repressionSUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PMLDNA end resection: many nucleases make light workThe structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functionsThe role of cullin 5-containing ubiquitin ligasesCytosolic Innate Immune Sensing and Signaling upon InfectionViral Mimicry to Usurp Ubiquitin and SUMO Host PathwaysNot All DDRs Are Created Equal: Non-Canonical DNA Damage ResponsesThe DNA damage response induced by infection with human cytomegalovirus and other virusesChemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promisingA Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor SuppressorsAdenovirus Early Proteins and Host SumoylationMYC activation associated with the integration of HPV DNA at the MYC locus in genital tumorsAncient and recent adaptive evolution of primate non-homologous end joining genesHuman papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiationThe Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage ResponseAdenovirus type 5 early region 1B 55K oncoprotein-dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cellsThe effect of DNA-dependent protein kinase on adeno-associated virus replicationRole of RAD52 epistasis group genes in homologous recombination and double-strand break repairTip60 degradation by adenovirus relieves transcriptional repression of viral transcriptional activator EIA.SPOC1-mediated antiviral host cell response is antagonized early in human adenovirus type 5 infectionAdenovirus core protein VII protects the viral genome from a DNA damage response at early times after infection.Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage respoHerpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection.Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection.A role for MRE11, NBS1, and recombination junctions in replication and stable maintenance of EBV episomes.A role for E1B-AP5 in ATR signaling pathways during adenovirus infectionIdentification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments.E1B and E4 oncoproteins of adenovirus antagonize the effect of apoptosis inducing factorChromatin at the intersection of viral infection and DNA damageRelocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replicationNoise cancellation: viral fine tuning of the cellular environment for its own genome replication.An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus.Rapid evolution of BRCA1 and BRCA2 in humans and other primates.DNA repair proteins affect the lifecycle of herpes simplex virus 1.Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradationThe Mre11 complex is required for ATM activation and the G2/M checkpointHeterochromatin silencing of p53 target genes by a small viral protein.
P2860
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P2860
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex.
@en
type
label
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex.
@en
prefLabel
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex.
@en
P2860
P356
P1433
P1476
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex.
@en
P2093
Christian T Carson
Matthew D Weitzman
P2860
P2888
P304
P356
10.1038/NATURE00863
P407
P577
2002-07-01T00:00:00Z
P6179
1035467868