Germ-line p53 mutations predispose to a wide spectrum of early-onset cancers.
about
Li-fraumeni syndromeSolid tumor second primary neoplasms: who is at risk, what can we do?p53 Acetylation: Regulation and ConsequencesBrain cancer mortality in an agricultural and a metropolitan region of Rio de Janeiro, Brazil: a population-based, age-period-cohort study, 1996-2010Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer TypesThe future role of personalized medicine in the treatment of glioblastoma multiformePOSTAR: a platform for exploring post-transcriptional regulation coordinated by RNA-binding proteinsEffects of MDM2, MDM4 and TP53 codon 72 polymorphisms on cancer risk in a cohort study of carriers of TP53 germline mutations.Germline mutations and polymorphisms in the origins of cancers in women.Constitutional haploinsufficiency of tumor suppressor genes in mentally retarded patients with microdeletions in 17p13.1.Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice.Rare multiple primary malignancies among surgical patients-a single surgical unit experienceBaseline results from the UK SIGNIFY study: a whole-body MRI screening study in TP53 mutation carriers and matched controls.Germline p53 mutations in a cohort with childhood sarcoma: sex differences in cancer riskZebrafish models of p53 functions.Development and translational imaging of a TP53 porcine tumorigenesis modelJoint effects of germ-line TP53 mutation, MDM2 SNP309, and gender on cancer risk in family studies of Li-Fraumeni syndrome.Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.Inherited germline TP53 mutation encodes a protein with an aberrant C-terminal motif in a case of pediatric adrenocortical tumorPrevalence of germline TP53 mutations in HER2+ breast cancer patients.Genomic landscape of paediatric adrenocortical tumours.A common variant of CDKN2A (p16) predisposes to breast cancer.Individual having a parent with early-onset gastric cancer may need screening at younger age.Elevated breast cancer risk among mothers of a population-based series of 2668 children with cancer.Primed for cancer: Li Fraumeni Syndrome and the pre-cancerous nicheHigh-grade serous ovarian cancer arises from fallopian tube in a mouse model.TP53 Silencing Bypasses Growth Arrest of BRAFV600E-Induced Lung Tumor Cells in a Two-Switch Model of Lung Tumorigenesis.A hypothesis-generating search for new genetic breast cancer syndromes--a national study in 803 Swedish families.Repression of mammary stem/progenitor cells by p53 is mediated by Notch and separable from apoptotic activity.Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism.Impaired TGF-β induced growth inhibition contributes to the increased proliferation rate of neural stem cells harboring mutant p53Timing and context: important considerations in the return of genetic results to research participants.Prevalence of germline TP53 mutations in a prospective series of unselected patients with adrenocortical carcinomaGenetic and functional analysis of a Li Fraumeni syndrome family in China.Gastric cancer in individuals with Li-Fraumeni syndromeEstrogen and progesterone induce persistent increases in p53-dependent apoptosis and suppress mammary tumors in BALB/c-Trp53+/- miceLi Fraumeni syndrome, cancer and senescence: a new hypothesis.Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome.Genetic counseling and testing for common hereditary breast cancer syndromes: a paper from the 2007 William Beaumont hospital symposium on molecular pathology.Survivin-directed RNA interference cocktail is a potent suppressor of tumour growth in vivo
P2860
Q22241780-BCFFAF7B-FC70-4656-8D94-D9CB37814493Q27026266-E4C97D65-CEA0-4AFB-B4B5-FCE6A41FFD33Q28085076-254818F0-46C3-406D-A884-43D52CC316B6Q28385747-82253076-6C2C-4771-B6C0-B441ABC07B15Q28388497-BC4779EE-60F1-4D7C-8745-3A0CCA451147Q28391635-20AADAA0-122C-4E71-BB42-B152DFFF0C23Q28584439-AA0B4949-BD0C-4AFD-A0FC-ED057E9AC9BEQ33593066-480A9FF6-3E00-48A7-A37E-F6C7B3412E58Q33606675-AED13A5F-4550-45A1-AE82-3FD4D790695CQ33620294-E514324E-D3C0-44F8-B2F4-3C2E3D938875Q33703779-3C721E7E-D7B4-4938-AB24-B1BBDF806DA0Q33768627-41F604DB-C94B-41A7-ABDD-73646BC7C167Q33844055-3AAB6417-7405-4879-A974-A0B17CA04C62Q33905119-C9950546-5FD5-47A9-8805-5E1C6C9846CAQ34014685-39A7896D-1726-460B-9F8B-9022D4B99169Q34117482-8A1F76F9-CF7B-424B-8688-BCDCDF742885Q34324382-912B08AC-75CC-4704-A12F-7BA2CBCFE195Q34391423-B37F00D0-9793-4C4D-85F1-B0D588CF5F80Q34565153-082FD8CB-2EB9-453A-913D-6EBFEBCF126DQ34789542-E9E5F284-4AAC-4454-AEF5-71A2DE9E68D7Q35156692-EA9E6E3C-5F5A-4E26-BF48-5E758893CD5AQ35447197-D162F635-6CAF-45A5-83A8-2BF6C2C824BDQ35472998-F89F31BC-81AA-4148-A948-4066E83DBB2FQ35602214-EE8B23C2-AFF5-40AC-833F-26E85BC04715Q35717532-E7FFE7CA-0A36-43C3-AB4D-B40F2CAB4699Q35844827-25A96AEB-E299-4F9D-972E-D137DEA9B56CQ35920997-E5EC6C7A-EDAE-4AED-9412-7CC20C895BF1Q36108214-C5FD9B98-0A88-478F-8E3D-129757AC5BC7Q36113210-85924303-A8FD-4ED4-BE33-FC0BFFDEF136Q36210940-5928321C-B5C0-4A0F-A0F6-0B9D40EC8D5EQ36420175-A51E55C4-6159-450E-AF03-E431CC5FA25FQ36470928-51AF9234-8938-4ED3-88EC-93DB0390B100Q36508843-43800F1D-8401-4D81-8E35-68015E700608Q36512100-41180D18-35F5-4A47-A675-7B63E335B0CDQ36678769-C418E670-82FF-4471-901C-268097AC4F65Q36787334-C3DD19B3-BF7A-43F4-91A9-CC143603A0BBQ36797708-ED9F2DD8-45F6-429F-ABAE-4AF00278A0B2Q36837569-5E9C59F3-3950-453C-991A-57A99D523D43Q36843211-14CDDA59-0F4F-4B1B-A8FE-F79AADFCEFD1Q36930279-CD76155E-BACC-4084-97FC-E01BB6F4A289
P2860
Germ-line p53 mutations predispose to a wide spectrum of early-onset cancers.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Germ-line p53 mutations predispose to a wide spectrum of early-onset cancers.
@en
type
label
Germ-line p53 mutations predispose to a wide spectrum of early-onset cancers.
@en
prefLabel
Germ-line p53 mutations predispose to a wide spectrum of early-onset cancers.
@en
P2093
P1476
Germ-line p53 mutations predispose to a wide spectrum of early-onset cancers
@en
P2093
P577
2001-02-01T00:00:00Z