Cationic interactions at the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2 alpha-carbomethoxy-3 alpha-(4-fluorophenyl)tropane.

Cationic interactions at the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2 alpha-carbomethoxy-3 alpha-(4-fluorophenyl)tropane.

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http://www.wikidata.org/entity/Q40724489
Recognition of psychostimulants, antidepressants, and other inhibitors of synaptic neurotransmitter uptake by the plasma membrane monoamine transportersInsights from molecular dynamics: the binding site of cocaine in the dopamine transporter and permeation pathways of substrates in the leucine and dopamine transporters.Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability.Interaction of catechol and non-catechol substrates with externally or internally facing dopamine transporters.Dopamine release mediated by the dopamine transporter, facts and consequences.Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.Interaction between dopamine and its transporter: role of intracellular sodium ions and membrane potential.Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding.Evidence for distinct sodium-, dopamine-, and cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine transporter.
P2860

Cationic interactions at the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2 alpha-carbomethoxy-3 alpha-(4-fluorophenyl)tropane.

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http://www.wikidata.org/entity/Q40724489
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Cationic interactions at the h ...... alpha-(4-fluorophenyl)tropane.
@en
type
label
Cationic interactions at the h ...... alpha-(4-fluorophenyl)tropane.
@en
prefLabel
Cationic interactions at the h ...... alpha-(4-fluorophenyl)tropane.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P356
P1433
P1476
Cationic interactions at the h ...... alpha-(4-fluorophenyl)tropane.
@en
P2093
P2860
P304
P31
P356
10.1046/J.1471-4159.2002.00941.X
P407
P433
P478
P577
P5875
P698