The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells.
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Glycogen synthase kinase 3: a point of convergence for the host inflammatory responseThe kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAsUpregulation of RGS4 expression by IL-1beta in colonic smooth muscle is enhanced by ERK1/2 and p38 MAPK and inhibited by the PI3K/Akt/GSK3beta pathwayInflammation, obesity, and thrombosisHyperlipidemia, tissue factor, coagulation, and simvastatinRecent advances in drug eluting stentsInterleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signalingThe Immunomodulatory Functions of Diacylglycerol Kinase ζThe Cytolethal Distending Toxin Contributes to Microbial Virulence and Disease Pathogenesis by Acting As a Tri-Perditious ToxinMycobacterium tuberculosis lipoarabinomannan-mediated IRAK-M induction negatively regulates Toll-like receptor-dependent interleukin-12 p40 production in macrophagesInhibition of phosphoinositol 3 kinase contributes to nanoparticle-mediated exaggeration of endotoxin-induced leukocyte procoagulant activityThe principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory statesRapamycin regulates the expression and activity of Krüppel-like transcription factor 2 in human umbilical vein endothelial cellsResveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cellsFine tuning inflammation at the front door: macrophage complement receptor 3-mediates phagocytosis and immune suppression for Francisella tularensisPhosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophagesB-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3KMyeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharidePhosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lambliaThe p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.Beta-(1-->3)-D-glucan modulates DNA binding of nuclear factors kappaB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratioInterleukin-10 suppression of myeloid cell activation--a continuing puzzle.NF-kappaB activation by Helicobacter pylori requires Akt-mediated phosphorylation of p65High-throughput screening for TLR3-IFN regulatory factor 3 signaling pathway modulators identifies several antipsychotic drugs as TLR inhibitors.Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis.Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells.Genkwanin inhibits proinflammatory mediators mainly through the regulation of miR-101/MKP-1/MAPK pathway in LPS-activated macrophages.Leishmania donovani isolates with antimony-resistant but not -sensitive phenotype inhibit sodium antimony gluconate-induced dendritic cell activation.Toll-like receptor 2 is required for opioids-induced neuronal apoptosis11β-HSD1 modulates LPS-induced innate immune responses in adipocytes by altering expression of PTEN.Insulin modulates the inflammatory granulocyte response to streptococci via phosphatidylinositol 3-kinase.Signaling pathways involved in LPS induced TNFalpha production in human adipocytes.Upregulation of tissue factor in monocytes by cleaved high molecular weight kininogen is dependent on TNF-alpha and IL-1betaGenetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages.The Myosin II Inhibitor, Blebbistatin, Ameliorates FeCl3-induced Arterial Thrombosis via the GSK3β-NF-κB Pathway.Insulin activation of the phosphatidylinositol 3-kinase/protein kinase B (Akt) pathway reduces lipopolysaccharide-induced inflammation in miceTLR2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide 3-kinase-dependent mechanism.PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes.Atorvastatin improves survival in septic rats: effect on tissue inflammatory pathway and on insulin signaling.IFN-beta production by TLR4-stimulated innate immune cells is negatively regulated by GSK3-beta.
P2860
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P2860
The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
The phosphatidylinositol 3-kin ...... tors in human monocytic cells.
@en
type
label
The phosphatidylinositol 3-kin ...... tors in human monocytic cells.
@en
prefLabel
The phosphatidylinositol 3-kin ...... tors in human monocytic cells.
@en
P356
P1476
The phosphatidylinositol 3-kin ...... tors in human monocytic cells.
@en
P2093
Mausumee Guha
Nigel Mackman
P304
32124-32132
P356
10.1074/JBC.M203298200
P407
P577
2002-06-06T00:00:00Z