Cardiomyocyte-specific gene expression following recombinant adeno-associated viral vector transduction.
about
Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repMicroRNA-regulated viral vectors for gene therapyNormal targeting of a tagged Kv1.5 channel acutely transfected into fresh adult cardiac myocytes by a biolistic methodCardiac-selective expression of extracellular superoxide dismutase after systemic injection of adeno-associated virus 9 protects the heart against post-myocardial infarction left ventricular remodeling.A single direct injection into the left ventricular wall of an adeno-associated virus 9 (AAV9) vector expressing extracellular superoxide dismutase from the cardiac troponin-T promoter protects mice against myocardial infarction.Systemic delivery of shRNA by AAV9 provides highly efficient knockdown of ubiquitously expressed GFP in mouse heart, but not liver.Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution.Role of cyclic AMP-dependent kinase response element-binding protein in recombinant adeno-associated virus-mediated transduction of heart muscle cells.Targeting the cell cycle machinery for the treatment of cardiovascular disease.AAV vectors for cardiac gene transfer: experimental tools and clinical opportunities.Cardiac overexpression of 8-oxoguanine DNA glycosylase 1 protects mitochondrial DNA and reduces cardiac fibrosis following transaortic constrictionTissue specific promoters improve specificity of AAV9 mediated transgene expression following intra-vascular gene delivery in neonatal mice.Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failureAn emerging adeno-associated viral vector pipeline for cardiac gene therapyRecombinant adeno-associated virus serotype 9 in a mouse model of atherosclerosis: Determination of the optimal expression time in vivo.Promise of adeno-associated virus as a gene therapy vector for cardiovascular diseases.Utility of vascular endothelial specific peptides for enhancement of adeno-associated virus-mediated gene transfer.Gene-therapy delivery strategies in cardiology.Analysis of angiogenesis induced by local IGF-1 expression after myocardial infarction using microSPECT-CT imaging.Targeting transgene to the heart and liver with AAV9 by different promoters.Cell type-specific functions of the lysosomal protease cathepsin L in the heart.The single-strand DNA/RNA-binding protein, Purbeta, regulates serum response factor (SRF)-mediated cardiac muscle gene expression.
P2860
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P2860
Cardiomyocyte-specific gene expression following recombinant adeno-associated viral vector transduction.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Cardiomyocyte-specific gene ex ...... ted viral vector transduction.
@en
type
label
Cardiomyocyte-specific gene ex ...... ted viral vector transduction.
@en
prefLabel
Cardiomyocyte-specific gene ex ...... ted viral vector transduction.
@en
P2093
P2860
P356
P1476
Cardiomyocyte-specific gene ex ...... ted viral vector transduction.
@en
P2093
Gordon S Huggins
Richard O Snyder
Ryuichi Aikawa
P2860
P304
18979-18985
P356
10.1074/JBC.M201257200
P407
P577
2002-03-11T00:00:00Z