Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction block.
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Propranolol blocks cardiac and neuronal voltage-gated sodium channelsSCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndromeIon Channels in the HeartCongenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A)Inherited conduction system abnormalities--one group of diseases, many genesThe cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardiumSodium channel mutations and susceptibility to heart failure and atrial fibrillationA common SCN5A polymorphism modulates the biophysical effects of an SCN5A mutation.Mutation-specific risk in two genetic forms of type 3 long QT syndrome.Survival of a Newborn with 2:1 Atrioventricular Block, Long QT Syndrome, and Torsades de PointesAn atypical case of Brugada syndrome.Inherited disorders of voltage-gated sodium channels.Mechanistic links between Na+ channel (SCN5A) mutations and impaired cardiac pacemaking in sick sinus syndrome.Dual variation in SCN5A and CACNB2b underlies the development of cardiac conduction disease without Brugada syndrome.SCN5A mutations in Brugada syndrome are associated with increased cardiac dimensions and reduced contractility.Ankyrin-G coordinates intercalated disc signaling platform to regulate cardiac excitability in vivoSCN5A rare variants in familial dilated cardiomyopathy decrease peak sodium current depending on the common polymorphism H558R and common splice variant Q1077del.Successful implantation of an intracardiac defibrillator in an infant with long QT syndrome and isolated noncompaction of the ventricular myocardium.Kinetic model of Nav1.5 channel provides a subtle insight into slow inactivation associated excitability in cardiac cells.Proposal for a new definition of congenital complete atrioventricular block.Deletion of PDK1 causes cardiac sodium current reduction in miceThe genetic basis for inherited forms of sinoatrial dysfunction and atrioventricular node dysfunctionMolecular biology of channelopathies: impact on diagnosis and treatment.Brief review of the recently described short QT syndrome and other cardiac channelopathies.Mechanisms of disease: current understanding and future challenges in Brugada syndrome.Sudden cardiac death and inherited arrhythmia syndromes.Genetic Analysis of SCN5A in Korean Patients Associated with Atrioventricular Conduction Block.Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation.Clinical aspects and physiopathology of Brugada syndrome: review of current concepts.Hypoplastic left heart syndrome with restrictive atrial septum and advanced heart block documented with a novel fetal electrocardiographic monitorSplicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.Role of sodium channels in propagation in heart muscle: how subtle genetic alterations result in major arrhythmic disorders.A common SCN5A polymorphism attenuates a severe cardiac phenotype caused by a nonsense SCN5A mutation in a Chinese family with an inherited cardiac conduction defectSodium channel mutation in irritable bowel syndrome: evidence for an ion channelopathy.Interpreting genetic effects through models of cardiac electromechanics.Reduced Penetrance and Variable Expression of SCN5A Mutations and the Importance of Co-inherited Genetic Variants: Case Report and Review of the Literature.Sodium channel haploinsufficiency and structural change in ventricular arrhythmogenesis.The late sodium current in heart failure: pathophysiology and clinical relevance.Relative contribution of changes in sodium current versus intercellular coupling on reentry initiation in 2-dimensional preparations of plakophilin-2-deficient cardiac cellsAutoimmune channelopathies as a novel mechanism in cardiac arrhythmias.
P2860
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P2860
Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction block.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Clinical, genetic, and biophys ...... oventricular conduction block.
@en
type
label
Clinical, genetic, and biophys ...... oventricular conduction block.
@en
prefLabel
Clinical, genetic, and biophys ...... oventricular conduction block.
@en
P2093
P356
P1433
P1476
Clinical, genetic, and biophys ...... oventricular conduction block.
@en
P2093
Alfred L George
D Woodrow Benson
Dao W Wang
Jeffrey R Balser
Prakash C Viswanathan
P304
P356
10.1161/HC0302.102592
P407
P577
2002-01-01T00:00:00Z