Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase.
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The structure of human 15-lipoxygenase-2 with a substrate mimicThe structure of human 5-lipoxygenaseCoactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 productionThe organization and consequences of eicosanoid signalingA Covalent Linker Allows for Membrane Targeting of an Oxylipin Biosynthetic Complex † ‡Structure of a Calcium-dependent 11R-Lipoxygenase Suggests a Mechanism for Ca2+ RegulationLipoxygenase pathways in Homo neanderthalensis: functional comparison with Homo sapiens isoformsThe structural basis for specificity in lipoxygenase catalysis.Evidence for convergent evolution in the signaling properties of a choanoflagellate tyrosine kinaseThe C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1.The N-terminal domain of the reticulocyte-type 15-lipoxygenase is not essential for enzymatic activity but contains determinants for membrane binding.Very long-chain fatty acid accumulation causes lipotoxic response via 5-lipoxygenase in cerebral adrenoleukodystrophy.Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesisLocation, location, location: compartmentalization of early events in leukotriene biosynthesis.Dimerization of human 5-lipoxygenase.Cellular arachidonate-releasing function of novel classes of secretory phospholipase A2s (groups III and XII).Membrane fluidity is a key modulator of membrane binding, insertion, and activity of 5-lipoxygenaseMolecular modeling of the membrane targeting of phospholipase C pleckstrin homology domains.Suppression of oxidative stress and 5-lipoxygenase activation by edaravone improves depressive-like behavior after concussion.Membrane-binding and activation mechanism of PTEN.2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52)--a novel type of 5-lipoxygenase inhibitor with favourable molecular pharmacology and efficacy in vivoCytosolic phospholipase A₂: physiological function and role in disease.Structural and Functional Analysis of Calcium Ion Mediated Binding of 5-Lipoxygenase to NanodiscsIdentification and Characterization of a New Protein Isoform of Human 5-LipoxygenaseA structure-based protocol for learning the family-specific mechanisms of membrane-binding domains.The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer.Improving protein crystal quality by selective removal of a Ca(2+)-dependent membrane-insertion loop5-Lipoxygenase-activating protein rescues activity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formation5-Lipoxygenase: mechanisms of regulation.Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.Molecular Dynamics Study on the Apo- and Holo-forms of 5-Lipoxygenase.Novel leukotriene biosynthesis inhibitors (2012-2016) as anti-inflammatory agents.Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans.Membrane-docking loops of the cPLA2 C2 domain: detailed structural analysis of the protein-membrane interface via site-directed spin-labeling.Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta.Low density lipoprotein receptor-related protein-mediated membrane translocation of 12/15-lipoxygenase is required for oxidation of low density lipoprotein by macrophages.Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox.The molecular basis of differential subcellular localization of C2 domains of protein kinase C-alpha and group IVa cytosolic phospholipase A2.Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSIS
P2860
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P2860
Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Molecular basis of the specifi ...... like domain of 5-lipoxygenase.
@en
type
label
Molecular basis of the specifi ...... like domain of 5-lipoxygenase.
@en
prefLabel
Molecular basis of the specifi ...... like domain of 5-lipoxygenase.
@en
P2093
P2860
P356
P1476
Molecular basis of the specifi ...... like domain of 5-lipoxygenase.
@en
P2093
Colin D Funk
Diana Murray
Shilpa Kulkarni
Sudipto Das
Wonhwa Cho
P2860
P304
13167-13174
P356
10.1074/JBC.M112393200
P407
P577
2002-01-16T00:00:00Z