Desensitization of cell signalling mediated by phosphoinositidase C.
about
Phosphorylation and regulation of a Gq/11-coupled receptor by casein kinase 1alphaDifferential regulation of the uridine nucleotide-activated P2Y4 and P2Y6 receptors. SER-333 and SER-334 in the carboxyl terminus are involved in agonist-dependent phosphorylation desensitization and internalization of the P2Y4 receptorIdentification of the major phosphorylation sites in human C5a anaphylatoxin receptor in vivoHomologous and heterologous uncoupling of muscarinic M(3) and alpha(1B) adrenoceptors to Galpha(q/11) in SH-SY5Y human neuroblastoma cellsHuman muscarinic receptors expressed in A9L and CHO cells: activation by full and partial agonistsDepletion-activated calcium current is inhibited by protein kinase in RBL-2H3 cells.Agonist-induced desensitization of histamine H1 receptor-mediated inositol phospholipid hydrolysis in human umbilical vein endothelial cells.Modulatory effects of NMDA on phosphoinositide responses evoked by the metabotropic glutamate receptor agonist 1S,3R-ACPD in neonatal rat cerebral cortex.Inositol 1,4,5-trisphosphate receptor down-regulation is activated directly by inositol 1,4,5-trisphosphate binding. Studies with binding-defective mutant receptors.Lack of a C-terminal tail in the mammalian gonadotropin-releasing hormone receptor confers resistance to agonist-dependent phosphorylation and rapid desensitization.Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors.Acute desensitization of phospholipase C-coupled muscarinic M3 receptors but not gonadotropin-releasing hormone receptors co-expressed in alphaT3-1 cells: implications for mechanisms of rapid desensitization.Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells.Decline of the calcium response on successive stimulation of a rat brain endothelial cell P2U purinoceptor.Desensitization of thyrotropin-releasing hormone receptor-mediated responses involves multiple steps.Desensitization of P2U receptor in neuronal cell line. Different control by the agonists ATP and UTP, as demonstrated by single-cell Ca2+ responses.Desensitization of gonadotropin-releasing hormone action in alphaT3-1 cells due to uncoupling of inositol 1,4,5-trisphosphate generation and Ca2+ mobilization.Pharmacological characterization of desensitization in a human mGlu1 alpha-expressing non-neuronal cell line co-transfected with a glutamate transporter.Contrasting effects of phorbol ester and agonist-mediated activation of protein kinase C on phosphoinositide and Ca2+ signalling in a human neuroblastomadelta- and mu-opioid receptor mobilization of intracellular calcium in SH-SY5Y human neuroblastoma cellsAgonist regulation of alpha 1B-adrenergic receptor subcellular distribution and function.Shear stress-induced [Ca2+]i transients and oscillations in mouse fibroblasts are mediated by endogenously released ATP.Absence of rapid desensitization of the mouse gonadotropin-releasing hormone receptor.Quantitative comparisons of muscarinic and bradykinin receptor-mediated Ins (1,4,5)P3 accumulation and Ca2+ signalling in human neuroblastoma cells.Relationship between agonist binding, phosphorylation and immunoprecipitation of the m3-muscarinic receptor, and second messenger responses.Characterization of metabotropic glutamate receptor-mediated facilitation of N-methyl-D-aspartate depolarization of neocortical neurones.BMS-180560, an insurmountable inhibitor of angiotensin II-stimulated responses: comparison with losartan and EXP3174.Role of sarcoplasmic/endoplasmic-reticulum Ca2+-ATPases in mediating Ca2+ waves and local Ca2+-release microdomains in cultured glia.Down-regulation of types I, II and III inositol 1,4,5-trisphosphate receptors is mediated by the ubiquitin/proteasome pathwayPhosphorylation of a phosphoinositidase C-linked muscarinic receptor by a novel kinase distinct from beta-adrenergic receptor kinase.The histamine H1 receptor in GT1-7 neuronal cells is regulated by calcium influx and KN-62, a putative inhibitor of calcium/calmodulin protein kinase II.Desensitization and resensitization of human platelets to 5-hydroxytryptamine at the level of signal transduction.Heterologous desensitization of bombesin- and vasopressin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts.Cyclic GMP regulates activation of phosphoinositidase C by bradykinin in sensory neurons.Complex relationship between Ins(1,4,5)P3 accumulation and Ca2+ -signalling in a human neuroblastoma reveled by cellular differentiation.Carbachol-stimulated Ca2+ increase in single neuroblastoma SH-SY5Y cells: effects of ethanol.Gq pathway desensitizes chemotactic receptor-induced calcium signaling via inositol trisphosphate receptor down-regulation.Identification of a novel receptor kinase that phosphorylates a phospholipase C-linked muscarinic receptor.Regulation of transmembrane signaling by ganglioside GM1: interaction of anti-GM1 with Neuro2a cells.
P2860
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P2860
Desensitization of cell signalling mediated by phosphoinositidase C.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Desensitization of cell signalling mediated by phosphoinositidase C.
@en
type
label
Desensitization of cell signalling mediated by phosphoinositidase C.
@en
prefLabel
Desensitization of cell signalling mediated by phosphoinositidase C.
@en
P2093
P1476
Desensitization of cell signalling mediated by phosphoinositidase C.
@en
P2093
Nahorski SR
Wojcikiewicz RJ
P304
P356
10.1016/0165-6147(93)90131-3
P577
1993-07-01T00:00:00Z