Receptor proximity, not intermolecular orientation, is critical for triggering T-cell activation.
about
Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivityT Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility ComplexReconciling views on T cell receptor germline bias for MHCDynamic force spectroscopy of parallel individual Mucin1-antibody bonds.T cell receptor triggering by force.The SCHOOL of nature: I. Transmembrane signaling.Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection.T-cell activation by soluble MHC oligomers can be described by a two-parameter binding model.Bi-specific MHC heterodimers for characterization of cross-reactive T cellsEvidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling.Nanoscale ligand spacing influences receptor triggering in T cells and NK cellsAn evolutionary and structural perspective on T cell antigen receptor function.Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response.Insights into T cell recognition of antigen: significance of two-dimensional kinetic parametersFunctional development of the T cell receptor for antigenA mechanism for SRC kinase-dependent signaling by noncatalytic receptors.T cell activation is determined by the number of presented antigens.Functional anatomy of T cell activation and synapse formation.Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes.Interactions of mucins with the Tn or Sialyl Tn cancer antigens including MUC1 are due to GalNAc-GalNAc interactions.CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers.TCR Signaling Emerges from the Sum of Many PartsDual Constant Domain-Fab: A novel strategy to improve half-life and potency of a Met therapeutic antibody.A window of opportunity for cooperativity in the T Cell Receptor.Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering
P2860
Q27333772-E19AB2E2-5713-47F3-AD61-3210E6DD8A2CQ27675661-58721653-BCA5-4AB0-BBBB-8CAB814885A4Q28270580-9BDBF500-E4FC-4D7F-B496-D43142ECECFCQ33226563-42A9BF1E-9D58-494E-8E16-CD9F1C485076Q33348048-578675BA-0551-4884-B2B1-34408A26F6A5Q33351190-87F78AA5-6C6B-466A-8075-9F0188A77830Q33902324-66E8C445-CE29-4593-B643-21DBC1AC1CEEQ34176726-7B1DDFC2-7AD5-4005-8791-5259E3737BAFQ34236896-DFD076C0-4349-4514-8FB1-E278927A6486Q34368920-CFC01D93-858B-4897-9870-D37D77237BAEQ34886056-6925621F-7EAF-4FA8-B262-63BBB2DF238AQ35076666-F89D805A-7503-4D17-9525-20D92A27BE37Q35130764-05A89175-8750-4E35-97B8-AEA3217D4920Q35927615-49997A98-7BAA-421A-A94B-F5EFCC12F52CQ36951583-1A90B530-F376-4324-9E85-FE1F17B84156Q37150264-EC055BCF-04FC-4F27-95BC-32B6506EE181Q37308616-33B45175-A751-4128-AC8F-E8AEB7BD2408Q37646737-65397AF4-215D-4787-B872-E71D6E07F5E2Q37953322-1491575A-EF39-45A7-9FE7-9A1B3CC2A546Q39696121-9B055B6B-15C2-4A57-A9B9-F19B6EEE3BF6Q40439959-318C13D1-D4A7-4C06-8933-6733F4B72040Q42212300-D86B5514-4E51-48F5-B37C-7D25486996FCQ42282846-E0312E81-3F49-443E-B3E3-54568D6F6C7DQ55475768-686B958C-613B-4AAE-8C72-48729F638CD6Q57961679-5AB4C5B3-31CC-457D-BF7F-DD03E076556C
P2860
Receptor proximity, not intermolecular orientation, is critical for triggering T-cell activation.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Receptor proximity, not interm ...... triggering T-cell activation.
@en
type
label
Receptor proximity, not interm ...... triggering T-cell activation.
@en
prefLabel
Receptor proximity, not interm ...... triggering T-cell activation.
@en
P2093
P2860
P356
P1476
Receptor proximity, not interm ...... triggering T-cell activation.
@en
P2093
P2860
P304
28068-28074
P356
10.1074/JBC.M103280200
P407
P577
2001-05-30T00:00:00Z