Attenuation of adhesion-dependent signaling and cell spreading in transformed fibroblasts lacking protein tyrosine phosphatase-1B.
about
TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1BRegulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblastsCoordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeletonThe protein tyrosine phosphatase HePTP regulates nuclear translocation of ERK2 and can modulate megakaryocytic differentiation of K562 cellsPhosphorylated alpha-actinin and protein-tyrosine phosphatase 1B coregulate the disassembly of the focal adhesion kinase x Src complex and promote cell migrationClosing in on the biological functions of Fps/Fes and FerProtein tyrosine phosphatase 1B participates in the down-regulation of erythropoietin receptor signallingThe role of protein-tyrosine phosphatase 1B in integrin signalingPTP1B regulates cortactin tyrosine phosphorylation by targeting Tyr446PTP-1B is an essential positive regulator of platelet integrin signalingInvestigation of protein-tyrosine phosphatase 1B function by quantitative proteomicsThe role of the C-terminal domain of protein tyrosine phosphatase-1B in phosphatase activity and substrate bindingFunctional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signalingDifferential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphataseProtein tyrosine phosphatase 1B negatively regulates macrophage development through CSF-1 signaling.The role of protein tyrosine phosphatase 1B in Ras signalingER-bound protein tyrosine phosphatase PTP1B interacts with Src at the plasma membrane/substrate interfaceA novel role for protein tyrosine phosphatase 1B as a positive regulator of neuroinflammation.Targeting Inactive Enzyme Conformation: Aryl Diketoacid Derivatives as a New Class of PTP1B InhibitorsRegulation of cell adhesion by protein-tyrosine phosphatases. I. Cell-matrix adhesionTwo mechanisms activate PTPalpha during mitosisProtein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stressThe protein-tyrosine phosphatase DEP-1 modulates growth factor-stimulated cell migration and cell-matrix adhesionRole of protein-tyrosine phosphatase SHP2 in focal adhesion kinase down-regulation during neutrophil cathepsin G-induced cardiomyocytes anoikisCoordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTPEntamoeba histolytica-induced dephosphorylation in host cells.Caspase-3 regulates catalytic activity and scaffolding functions of the protein tyrosine phosphatase PEST, a novel modulator of the apoptotic response.Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.Targeting PTPs with small molecule inhibitors in cancer treatmentProtein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis.Protein tyrosine phosphatase 4A2 expression predicts overall and disease-free survival of human breast cancer and is associated with estrogen and progestin receptor status.Protein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling.Protein tyrosine phosphatases as drug targets: PTP1B and beyond.PTP alpha regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migrationPTP1B and TC-PTP: novel roles in immune-cell signaling.Protein tyrosine phosphatase function: the substrate perspective.Physiological signaling specificity by protein tyrosine phosphatases.Inhibition of a specific N-glycosylation activity results in attenuation of breast carcinoma cell invasiveness-related phenotypes: inhibition of epidermal growth factor-induced dephosphorylation of focal adhesion kinase.Inhibition of PTP1B disrupts cell-cell adhesion and induces anoikis in breast epithelial cellsPTP1B expression contributes to gastric cancer progression.
P2860
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P2860
Attenuation of adhesion-dependent signaling and cell spreading in transformed fibroblasts lacking protein tyrosine phosphatase-1B.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Attenuation of adhesion-depend ...... otein tyrosine phosphatase-1B.
@en
type
label
Attenuation of adhesion-depend ...... otein tyrosine phosphatase-1B.
@en
prefLabel
Attenuation of adhesion-depend ...... otein tyrosine phosphatase-1B.
@en
P2093
P2860
P356
P1476
Attenuation of adhesion-depend ...... rotein tyrosine phosphatase-1B
@en
P2093
P2860
P304
25848-25855
P356
10.1074/JBC.M009734200
P407
P50
P577
2001-05-09T00:00:00Z