Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia.
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Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowthInhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophreniaDevelopmental origins of brain disorders: roles for dopamineDrug elucidation: invertebrate genetics sheds new light on the molecular targets of CNS drugs.The DISC locus in psychiatric illnessA frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorderDISC1: Structure, Function, and Therapeutic Potential for Major Mental IllnessDISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowthWiki-pi: a web-server of annotated human protein-protein interactions to aid in discovery of protein functionSearching human brain for mechanisms of psychiatric disorders. Implications for studies on schizophrenia.Potential primary roles of glial cells in the mechanisms of psychiatric disorders.Neurodevelopmental animal models of schizophrenia: role in novel drug discovery and developmentPre-clinical models of neurodevelopmental disorders: focus on the cerebellumIs lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses.Animal models of schizophrenia.New frontiers in animal research of psychiatric illnessPrenatal interaction of mutant DISC1 and immune activation produces adult psychopathology.Maternal genetic mutations as gestational and early life influences in producing psychiatric disease-like phenotypes in mice.Animal models of gene-environment interactions in schizophrenia.Reduced NMDAR1 expression in the Sp4 hypomorphic mouse may contribute to endophenotypes of human psychiatric disordersA novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.Increased stathmin1 expression in the dentate gyrus of mice causes abnormal axonal arborizationsDysbindin regulates the transcriptional level of myristoylated alanine-rich protein kinase C substrate via the interaction with NF-YB in mice brain.Genetic copy number variants in sib pairs both affected with schizophrenia.Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorderMeta-analyses of 10 polymorphisms associated with the risk of schizophrenia.Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.Primate models of schizophrenia: future possibilities.The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders.The 2nd Schizophrenia International Research Society Conference, 10-14 April 2010, Florence, Italy: summaries of oral sessions.Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia.Schizophrenia interactome with 504 novel protein-protein interactionsPersonalized medicine in psychiatry: problems and promises.Mutant DISC1 affects methamphetamine-induced sensitization and conditioned place preference: a comorbidity model.DISC1 (disrupted-in-schizophrenia-1) regulates differentiation of oligodendrocytesDetection of chromosomal breakpoints in patients with developmental delay and speech disordersExpression of mutant human DISC1 in mice supports abnormalities in differentiation of oligodendrocytes.The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.Progress toward discovery of susceptibility genes for bipolar manic-depressive illness and schizophrenia.
P2860
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P2860
Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Genomic structure and localisa ...... egregating with schizophrenia.
@en
type
label
Genomic structure and localisa ...... egregating with schizophrenia.
@en
prefLabel
Genomic structure and localisa ...... egregating with schizophrenia.
@en
P2093
P2860
P356
P1433
P1476
Genomic structure and localisa ...... segregating with schizophrenia
@en
P2093
Anderson S
Arveiler B
Blackwood DH
Christie S
Hsiao-Wei Loh D
P2860
P2888
P304
P356
10.1038/SJ.MP.4000784
P407
P577
2001-03-01T00:00:00Z