A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder - Wikidata - wikimedia - TriplyDB

A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder

A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder

http://www.wikidata.org/entity/Q28254976

about

Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios Mouse Genetic Models of Human Brain Disorders Phosphodiesterase Inhibition and Regulation of Dopaminergic Frontal and Striatal Functioning: Clinical Implications Associating schizophrenia, long non-coding RNAs and neurostructural dynamics Gene × Environment Interactions in Schizophrenia: Evidence from Genetic Mouse Models Molecular genetic studies of schizophrenia The DISC locus in psychiatric illness DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development Animal models of gene-environment interaction in schizophrenia: A dimensional perspective.PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosis Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology.Contribution of nonprimate animal models in understanding the etiology of schizophrenia.Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes.Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology.Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.Linking neurodevelopmental and synaptic theories of mental illness through DISC1 Families with the risk allele of DISC1 reveal a link between schizophrenia and another component of the same molecular pathway, NDE1.The genetic deconstruction of psychosis Analysis of whole genome biomarker expression in blood and brain Deletion polymorphism of Disc1 is common to all 129 mouse substrains: implications for gene-targeting studies of brain function.Mutant DISC1 affects methamphetamine-induced sensitization and conditioned place preference: a comorbidity model.Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes Nature and nurture in neuropsychiatric genetics: where do we stand?Elevated DISC1 transcript levels in PBMCs during acute psychosis in patients with schizophrenia.Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia.Imaging genomics and response to treatment with antipsychotics in schizophrenia.Schizophrenia genetics: uncovering positional candidate genes.Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β.Deep resequencing and association analysis of schizophrenia candidate genes.DISC1 genetics, biology and psychiatric illness Schizophrenia in translation: disrupted in schizophrenia (DISC1): integrating clinical and basic findings.The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model.Molecular genetics of bipolar disorder and depression.Stimulation of Synaptic Vesicle Exocytosis by the Mental Disease Gene DISC1 is Mediated by N-Type Voltage-Gated Calcium Channels.Simultaneous effects on parvalbumin-positive interneuron and dopaminergic system development in a transgenic rat model for sporadic schizophrenia.Disrupted in schizophrenia 1 (DISC1) L100P mutants have impaired activity-dependent plasticity in vivo and in vitro.

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A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder

http://www.wikidata.org/entity/Q28254976

description

2005 nî lūn-bûn

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2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2005 թվականի օգոստոսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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A frameshift mutation in Disru ...... a and schizoaffective disorder

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A frameshift mutation in Disru ...... a and schizoaffective disorder

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A frameshift mutation in Disru ...... a and schizoaffective disorder

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A frameshift mutation in Disru ...... a and schizoaffective disorder

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A frameshift mutation in Disru ...... a and schizoaffective disorder

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A frameshift mutation in Disru ...... a and schizoaffective disorder

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A frameshift mutation in Disru ...... a and schizoaffective disorder

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Molecular Psychiatry

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A frameshift mutation in Disru ...... a and schizoaffective disorder

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A Sawa

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C A Ross

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L E DeLisi

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P2860

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation

Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly

Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein

Disruption of two novel genes by a translocation co-segregating with schizophrenia

Yeast two-hybrid screens implicate DISC1 in brain development and function

Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth

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