CD4+ T cells from CD4C/HIVNef transgenic mice show enhanced activation in vivo with impaired proliferation in vitro but are dispensable for the development of a severe AIDS-like organ disease

CD4+ T cells from CD4C/HIVNef transgenic mice show enhanced activation in vivo with impaired proliferation in vitro but are dispensable for the development of a severe AIDS-like organ disease

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http://www.wikidata.org/entity/Q40815028
Oropharyngeal Candidiasis in HIV Infection: Analysis of Impaired Mucosal Immune Response to Candida albicans in Mice Expressing the HIV-1 TransgeneIncreased cardiovascular disease risk in the HIV-positive population on ART: potential role of HIV-Nef and TatThe Nef-mediated AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with increased Fas/FasL expression on T cells and T-cell death but is not prevented in Fas-, FasL-, tumor necrosis factor receptor 1-, or interleukDefective IL-17- and IL-22-dependent mucosal host response to Candida albicans determines susceptibility to oral candidiasis in mice expressing the HIV-1 transgene.Intracellular Nef detected in peripheral blood mononuclear cells from HIV patients.Repeated stimulation of CD4 effector T cells can limit their protective function.Altered immune response differentially enhances susceptibility to Cryptococcus neoformans and Cryptococcus gattii infection in mice expressing the HIV-1 transgene.Adult AIDS-like disease in a novel inducible human immunodeficiency virus type 1 Nef transgenic mouse model: CD4+ T-cell activation is Nef dependent and can occur in the absence of lymphophenia.Activation of p21-activated kinase 2 and its association with Nef are conserved in murine cells but are not sufficient to induce an AIDS-like disease in CD4C/HIV transgenic mice.Primary human immunodeficiency virus type 1 nef alleles show major differences in pathogenicity in transgenic mice.Selective expression of human immunodeficiency virus Nef in specific immune cell populations of transgenic mice is associated with distinct AIDS-like phenotypes.
P2860

CD4+ T cells from CD4C/HIVNef transgenic mice show enhanced activation in vivo with impaired proliferation in vitro but are dispensable for the development of a severe AIDS-like organ disease

Item
http://www.wikidata.org/entity/Q40815028
description
2004 nî lūn-bûn
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2004年の論文
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2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
CD4+ T cells from CD4C/HIVNef ...... severe AIDS-like organ disease
@en
type
label
CD4+ T cells from CD4C/HIVNef ...... severe AIDS-like organ disease
@en
prefLabel
CD4+ T cells from CD4C/HIVNef ...... severe AIDS-like organ disease
@en
P1433
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P2093
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P433
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CD4+ T cells from CD4C/HIVNef ...... severe AIDS-like organ disease
@en
P2093
P2860
P304
P31
P356
10.1128/JVI.78.10.5244-5257.2004
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