Inhibition of the MEK/ERK signaling pathway blocks a subset of B cell responses to antigen.
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The SH3-SAM adaptor HACS1 is up-regulated in B cell activation signaling cascadesExpression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomasThe B lymphocyte adaptor molecule of 32 kD (Bam32) regulates B cell antigen receptor signaling and cell survivalThe Immunomodulatory Functions of Diacylglycerol Kinase ζFcgamma receptor cross-linking stimulates cell proliferation of macrophages via the ERK pathway.Actin depolymerization transduces the strength of B-cell receptor stimulationDiacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responsesKidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.Mitogen-activated protein kinase signalling and ERK1/2 bistability in asthma.ERK1 is important for Th2 differentiation and development of experimental asthma.Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptorsCbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk.Role of protein tyrosine kinase and Erk1/2 activities in the Toll-like receptor 2-induced cellular activation of murine B cells by neisserial porin.Pivotal advance: CEACAM1 is a negative coreceptor for the B cell receptor and promotes CD19-mediated adhesion of B cells in a PI3K-dependent manner.Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells.Receptor crosstalk: reprogramming B cell receptor signalling to an alternate pathway results in expression and secretion of the autoimmunity-associated cytokine, osteopontinIncreased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients.MAP Kinase Cascades in Antigen Receptor Signaling and Physiology.Modulation of Ets-1 expression in B lymphocytes is dependent on the antigen receptor-mediated activation signals and cell cycle status.Spectrum of T-lymphocyte activities regulating allergic lung inflammation.Integration of signals from the B-cell antigen receptor and the IL-4 receptor leads to a cooperative shift in the cellular response axis.Ligation of CD44 leads to killing activity in human peripheral mononuclear cells via MAP kinase and tyrosine kinases.Immunomodulation of human B cells following treatment with intravenous immunoglobulins involves increased phosphorylation of extracellular signal-regulated kinases 1 and 2.The role of MAPKs in B cell receptor-induced down-regulation of Egr-1 in immature B lymphoma cells.Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models.CD45RA and RO isoforms have distinct effects on cytokine- and B-cell-receptor-mediated signalling in human B cells.Rituximab induces different but overlapping sets of genes in human B-lymphoma cell lines.The MEK inhibitor trametinib separates murine graft-versus-host disease from graft-versus-tumor effects.RasGRP1 sensitizes an immature B cell line to antigen receptor-induced apoptosis.Convergence of signaling pathways on the activation of ERK in B cells.Extracellular signal-regulated protein kinase 2 is required for efficient generation of B cells bearing antigen-specific immunoglobulin G.Differential role of reactive oxygen species in the activation of mitogen-activated protein kinases and Akt by key receptors on B-lymphocytes: CD40, the B cell antigen receptor, and CXCR4.Requirement for a hsp90 chaperone-dependent MEK1/2-ERK pathway for B cell antigen receptor-induced cyclin D2 expression in mature B lymphocytes.Enhanced B-cell activation mediated by TLR4 and BCR crosstalk.Rapid changes in hippocampal CA1 pyramidal cell function via pre- as well as postsynaptic membrane mineralocorticoid receptors.The reduction of EPSC amplitude in CA1 pyramidal neurons by the peroxynitrite donor SIN-1 requires Ca2+ influx via postsynaptic non-L-type voltage gated calcium channels.Integrative genomic profiling reveals conserved genetic mechanisms for tumorigenesis in common entities of non-Hodgkin's lymphoma.Transforming growth factor β1 (TGFβ1) regulates CD44V6 expression and activity through extracellular signal-regulated kinase (ERK)-induced EGR1 in pulmonary fibrogenic fibroblasts.CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes.Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease.
P2860
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P2860
Inhibition of the MEK/ERK signaling pathway blocks a subset of B cell responses to antigen.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Inhibition of the MEK/ERK sign ...... f B cell responses to antigen.
@en
type
label
Inhibition of the MEK/ERK sign ...... f B cell responses to antigen.
@en
prefLabel
Inhibition of the MEK/ERK sign ...... f B cell responses to antigen.
@en
P2093
P1476
Inhibition of the MEK/ERK sign ...... f B cell responses to antigen.
@en
P2093
A A Mamchak
A L DeFranco
J D Richards
P304
P356
10.4049/JIMMUNOL.166.6.3855
P407
P577
2001-03-01T00:00:00Z