Microfluidic local perfusion chambers for the visualization and manipulation of synapses
about
Temporal gradients in microfluidic systems to probe cellular dynamics: a reviewCompartmentalized microchannel array for high-throughput analysis of single cell polarized growth and dynamics.The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugatesRecording large extracellular spikes in microchannels along many axonal sites from individual neuronsMicrofluidic neurite guidance to study structure-function relationships in topologically-complex population-based neural networks.Emerging Functions of Circular RNAsCompartmentalized Platforms for Neuro-Pharmacological ResearchSynergistic NGF/B27 gradients position synapses heterogeneously in 3D micropatterned neural culturesMitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and ParkinMeasuring action potential-evoked transmission at individual synaptic contactsMicro total analysis systems for cell biology and biochemical assaysA microfluidic platform for controlled biochemical stimulation of twin neuronal networks.Spatially selective photoconductive stimulation of live neurons.Low piconewton towing of CNS axons against diffusing and surface-bound repellents requires the inhibition of motor protein-associated pathways.Calpain-1 deletion impairs mGluR-dependent LTD and fear memory extinctionA role for dendritic mGluR5-mediated local translation of Arc/Arg3.1 in MEF2-dependent synapse eliminationUsing high-throughput barcode sequencing to efficiently map connectomes.NMDA receptors mediate synaptic competition in culture.Synapse microarray identification of small molecules that enhance synaptogenesis.Self-organizing circuit assembly through spatiotemporally coordinated neuronal migration within geometric constraintsAxonQuant: A Microfluidic Chamber Culture-Coupled Algorithm That Allows High-Throughput Quantification of Axonal Damage.The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imaging.IGF2BP3-mediated translation in cell protrusions promotes cell invasiveness and metastasis of pancreatic cancer.The central dogma decentralized: new perspectives on RNA function and local translation in neurons.Co-culture of neurons and glia in a novel microfluidic platformA versatile valve-enabled microfluidic cell co-culture platform and demonstration of its applications to neurobiology and cancer biology.Synapto-protective drugs evaluation in reconstructed neuronal network.Probing functional properties of nociceptive axons using a microfluidic culture system.Neurotrophin-mediated dendrite-to-nucleus signaling revealed by microfluidic compartmentalization of dendritesChemical biology strategies for posttranslational control of protein function.Combining microfluidics, optogenetics and calcium imaging to study neuronal communication in vitro.Rat embryonic hippocampus and induced pluripotent stem cell derived cultured neurons recover from laser-induced subaxotomy.Physiologically relevant organs on chips.Passive microfluidic chamber for long-term imaging of axon guidance in response to soluble gradients.Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression.Retinal synaptic regeneration via microfluidic guiding channels.Multi-compartment neuron-glia co-culture platform for localized CNS axon-glia interaction study.Group I metabotropic glutamate receptor-mediated gene transcription and implications for synaptic plasticity and diseases.Dendrosomatic Sonic Hedgehog Signaling in Hippocampal Neurons Regulates Axon Elongation.New perspectives on neuronal development via microfluidic environments.
P2860
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P2860
Microfluidic local perfusion chambers for the visualization and manipulation of synapses
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Microfluidic local perfusion chambers for the visualization and manipulation of synapses
@en
type
label
Microfluidic local perfusion chambers for the visualization and manipulation of synapses
@en
prefLabel
Microfluidic local perfusion chambers for the visualization and manipulation of synapses
@en
P2093
P2860
P1433
P1476
Microfluidic local perfusion chambers for the visualization and manipulation of synapses
@en
P2093
Anne M Taylor
Erin M Schuman
Hiroshi T Ito
Sally A Kim
P2860
P356
10.1016/J.NEURON.2010.03.022
P407
P577
2010-04-01T00:00:00Z