Characterization and subcellular localization of KCNQ1 with a heterozygous mutation in the C terminus.
about
Structural insight into KCNQ (Kv7) channel assembly and channelopathyMolecular pathogenesis of long QT syndrome type 1Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator which rescues LQTs mutantsTruncated KCNQ1 mutant, A178fs/105, forms hetero-multimer channel with wild-type causing a dominant-negative suppression due to trafficking defect.Long QT syndrome in South Africa: the results of comprehensive genetic screening.Apamin does not inhibit human cardiac Na+ current, L-type Ca2+ current or other major K+ currentsEmerging concepts in the pharmacogenomics of arrhythmias: ion channel trafficking.Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillationInherited arrhythmic disorders in Japan.A novel mutation in KCNQ1 associated with a potent dominant negative effect as the basis for the LQT1 form of the long QT syndrome.Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway.Trafficking-competent KCNQ1 variably influences the function of HERG long QT alleles.Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels.A structural requirement for processing the cardiac K+ channel KCNQ1.An LQT mutant minK alters KvLQT1 trafficking.Cellular mechanisms underlying the increased disease severity seen for patients with long QT syndrome caused by compound mutations in KCNQ1.
P2860
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P2860
Characterization and subcellular localization of KCNQ1 with a heterozygous mutation in the C terminus.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Characterization and subcellul ...... us mutation in the C terminus.
@en
type
label
Characterization and subcellul ...... us mutation in the C terminus.
@en
prefLabel
Characterization and subcellul ...... us mutation in the C terminus.
@en
P2093
P356
P1476
Characterization and subcellul ...... us mutation in the C terminus.
@en
P2093
Ninomiya T
Sasayama S
P304
P356
10.1006/JMCC.2000.1300
P577
2001-02-01T00:00:00Z