Cognition, mechanism, and evolutionary relationships in aminoacyl-tRNA synthetases.
about
Expression of a gene encoding a tRNA synthetase-like protein is enhanced in tumorigenic human myeloid leukemia cells and is cell cycle stage- and differentiation-dependentGenetic code in evolution: switching species-specific aminoacylation with a peptide transplant.Crystal structure of a human aminoacyl-tRNA synthetase cytokineCrystal structures that suggest late development of genetic code components for differentiating aromatic side chainsArchaea and the prokaryote-to-eukaryote transitionEvolutionary Limitation and Opportunities for Developing tRNA Synthetase Inhibitors with 5-Binding-Mode ClassificationUrzymology: experimental access to a key transition in the appearance of enzymes2.9 Å crystal structure of ligand-free tryptophanyl-tRNA synthetase: Domain movements fragment the adenine nucleotide binding siteThe 2 Å crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogueDivergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structureCrystal structure of human tryptophanyl-tRNA synthetase catalytic fragment: insights into substrate recognition, tRNA binding, and angiogenesis activityVirus-Encoded Aminoacyl-tRNA Synthetases: Structural and Functional Characterization of Mimivirus TyrRS and MetRSParadox of mistranslation of serine for alanine caused by AlaRS recognition dilemmaStructure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphateImportance of single molecular determinants in the fidelity of expanded genetic codesInternally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for RepurposingStructural Switch of Lysyl-tRNA Synthetase between Translation and TranscriptionATP-directed capture of bioactive herbal-based medicine on human tRNA synthetaseSide chain independent recognition of aminoacyl adenylates by the Hint1 transcription suppressorUnique domain appended to vertebrate tRNA synthetase is essential for vascular developmentThe first step of aminoacylation at the atomic level in histidyl-tRNA synthetaseSaccharomyces cerevisiae possesses a stress-inducible glycyl-tRNA synthetase gene.An unusual pattern of protein expression and localization of yeast alanyl-tRNA synthetase isoforms.An inserted region of leucyl-tRNA synthetase plays a critical role in group I intron splicing.Histidyl-tRNA synthetaseEvidence that two present-day components needed for the genetic code appeared after nucleated cells separated from eubacteriaBiochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug targetStructural phylogenomics retrodicts the origin of the genetic code and uncovers the evolutionary impact of protein flexibilityOne ancestor for two codes viewed from the perspective of two complementary modes of tRNA aminoacylationStructure-specific tRNA-binding protein from the extreme thermophile Aquifex aeolicusTrp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signalingThe phylogeny of proteobacteria: relationships to other eubacterial phyla and eukaryotesOverview of protein structural and functional folds.Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetaseGeneration of dominant selectable markers for resistance to pseudomonic acid by cloning and mutagenesis of the ileS gene from the archaeon Methanosarcina barkeri fusaro.Interdomain interactions in oligomeric enzymes: creation of asymmetry in homo-oligomers and role in metabolite channeling between active centers of hetero-oligomers.Detection of noncovalent tRNA.aminoacyl-tRNA synthetase complexes by matrix-assisted laser desorption/ionization mass spectrometry.The Rodin-Ohno hypothesis that two enzyme superfamilies descended from one ancestral gene: an unlikely scenario for the origins of translation that will not be dismissed.A single sequence context cannot satisfy all non-AUG initiator codons in yeast.Transfer RNA and human disease
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P2860
Cognition, mechanism, and evolutionary relationships in aminoacyl-tRNA synthetases.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Cognition, mechanism, and evolutionary relationships in aminoacyl-tRNA synthetases.
@en
type
label
Cognition, mechanism, and evolutionary relationships in aminoacyl-tRNA synthetases.
@en
prefLabel
Cognition, mechanism, and evolutionary relationships in aminoacyl-tRNA synthetases.
@en
P1476
Cognition, mechanism, and evolutionary relationships in aminoacyl-tRNA synthetases.
@en
P2093
Carter CW Jr
P304
P356
10.1146/ANNUREV.BI.62.070193.003435
P577
1993-01-01T00:00:00Z