Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection.
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IRF7: activation, regulation, modification and functionPhospholipid scramblase 1 potentiates the antiviral activity of interferonInterferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanismsPhosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defenseAntiviral actions of interferonsA novel Toll-like receptor that recognizes vesicular stomatitis virusImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionMiddle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak controlResistance to Rhabdoviridae Infection and Subversion of Antiviral ResponsesRoles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functionsPKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in NeuronsClassical Swine Fever Virus Interferes with Cellular Antiviral Defense: Evidence for a Novel Function of NproTranslational mini-review series on Toll-like receptors: recent advances in understanding the role of Toll-like receptors in anti-viral immunityWest Nile Virus-Induced Interferon Production Is Mediated by the Double-Stranded RNA-Dependent Protein Kinase PKRInterferon-inducible antiviral effectorsEnhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKRThe direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formationTranslation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylationEnhancement of replication of RNA viruses by ADAR1 via RNA editing and inhibition of RNA-activated protein kinaseSerine 18 phosphorylation of RAX, the PKR activator, is required for PKR activation and consequent translation inhibitionMechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosisDouble-stranded RNA-activated protein kinase regulates early innate immune responses during respiratory syncytial virus infectionDDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cellsAntiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA virusesResistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKRInfluenza A virus infections in swine: pathogenesis and diagnosis.Highly pathogenic avian influenza H5N1 virus delays apoptotic responses via activation of STAT3.PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial loadThe protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen.Prioritizing genes responsible for host resistance to influenza using network approachesAntiviral defense: interferons and beyondSmall interfering RNA profiling reveals key role of clathrin-mediated endocytosis and early endosome formation for infection by respiratory syncytial virusActivation of NF-kB pathway by virus infection requires Rb expression.Activation of an antiviral response in normal but not transformed mouse cells: a new determinant of minute virus of mice oncotropismmRNA vaccine delivery using lipid nanoparticles.Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling.Diversity in viral anti-PKR mechanisms: a remarkable case of evolutionary convergenceInduction of interferon and interferon signaling pathways by replication of defective interfering particle RNA in cells constitutively expressing vesicular stomatitis virus replication proteinsInnate immunity to influenza virus infection.In vitro blood cell responsiveness to IFN-α predicts clinical response independently of IL28B in hepatitis C virus genotype 1 infected patients.
P2860
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P2860
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Essential role for the dsRNA-d ...... e immunity to viral infection.
@en
type
label
Essential role for the dsRNA-d ...... e immunity to viral infection.
@en
prefLabel
Essential role for the dsRNA-d ...... e immunity to viral infection.
@en
P2093
P1433
P1476
Essential role for the dsRNA-d ...... e immunity to viral infection.
@en
P2093
Balachandran S
Pattnaik AK
Roberts PC
P304
P356
10.1016/S1074-7613(00)00014-5
P407
P577
2000-07-01T00:00:00Z