Independent expression of the transforming amino-terminal domain of SV40 large I antigen from an alternatively spliced third SV40 early mRNA.
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T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirusSimian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 bindingA truncated T antigen expressed from an alternatively spliced BK virus early mRNA.Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens.Complete nucleotide sequence of polyomavirus SA12.Enumeration of the simian virus 40 early region elements necessary for human cell transformationImpaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivoMerkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus.Discovery of STL polyomavirus, a polyomavirus of ancestral recombinant origin that encodes a unique T antigen by alternative splicing.Regions and activities of simian virus 40 T antigen that cooperate with an activated ras oncogene in transforming primary rat embryo fibroblasts.Viral oncogenes, noncoding RNAs, and RNA splicing in human tumor virusesCharacterization of T Antigens, Including Middle T and Alternative T, Expressed by the Human Polyomavirus Associated with Trichodysplasia Spinulosa.Removal of a small C-terminal region of JCV and SV40 large T antigens has differential effects on transformationT antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisSmall tumor antigen of polyomaviruses: role in viral life cycle and cell transformationA mouse model of uterine leiomyosarcomaDifferential expression of mRNAs for JC virus large and small tumor antigens in brain tissues from progressive multifocal leukoencephalopathy patients with and without AIDS.Surveillance mechanism linking Bub1 loss to the p53 pathway.A simian virus 40 large T-antigen segment containing amino acids 1 to 127 and expressed under the control of the rat elastase-1 promoter produces pancreatic acinar carcinomas in transgenic mice.Merkel cell polyomavirus: a newly discovered human virus with oncogenic potential.Regulation of gene expression in primate polyomaviruses.MCV and Merkel cell carcinoma: a molecular success story.Cooperation of simian virus 40 large and small T antigens in metabolic stabilization of tumor suppressor p53 during cellular transformation.Human polyoma JC virus minor capsid proteins, VP2 and VP3, enhance large T antigen binding to the origin of viral DNA replication: evidence for their involvement in regulation of the viral DNA replication.Loss of p19(ARF) eliminates the requirement for the pRB-binding motif in simian virus 40 large T antigen-mediated transformation.Polyomavirus T antigens: molecular chaperones for multiprotein complexes.pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppressionOverexpression of simian virus 40 small-T antigen blocks centrosome function and mitotic progression in human fibroblasts.Synergism of BARF1 with Ras induces malignant transformation in primary primate epithelial cells and human nasopharyngeal epithelial cells.A novel translational regulation function for the simian virus 40 large-T antigen geneSimian virus 40 small t antigen activates the carboxyl-terminal transforming p53-binding domain of large T antigen.Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations.Tiny T antigen: an autonomous polyomavirus T antigen amino-terminal domain.The kinetics of simian virus 40-induced progression of quiescent cells into S phase depend on four independent functions of large T antigen.Comparative analysis of SV40 17kT and LT function in vivo demonstrates that LT's C-terminus re-programs hepatic gene expression and is necessary for tumorigenesis in the liver.Viral Oncology: Molecular Biology and Pathogenesis.
P2860
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P2860
Independent expression of the transforming amino-terminal domain of SV40 large I antigen from an alternatively spliced third SV40 early mRNA.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Independent expression of the ...... spliced third SV40 early mRNA.
@en
type
label
Independent expression of the ...... spliced third SV40 early mRNA.
@en
prefLabel
Independent expression of the ...... spliced third SV40 early mRNA.
@en
P2093
P2860
P1433
P1476
Independent expression of the ...... spliced third SV40 early mRNA
@en
P2093
Knippschild U
P2860
P304
P356
10.1002/J.1460-2075.1993.TB06162.X
P407
P577
1993-12-01T00:00:00Z