The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251.
about
Inhibition of cell growth by EGR-1 in human primary cultures from malignant gliomaHypertrophic scar contracture is mediated by the TRPC3 mechanical force transducer via NFkB activation.Trichomonas vaginalis adherence mediates differential gene expression in human vaginal epithelial cells.Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activator activity via up-regulation of EGR1.Global Egr1-miRNAs binding analysis in PMA-induced K562 cells using ChIP-Seq.Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape.Suppression of Egr-1 transcription through targeting of the serum response factor by oncogenic H-RasEstrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status.Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescenceIdentification of STAT3-independent regulatory effects for protein inhibitor of activated STAT3 by binding to novel transcription factors.WT1/EGR1-mediated control of STIM1 expression and function in cancer cellsIdentification of an Efficient Gene Expression Panel for Glioblastoma Classification.The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin.Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1).Computational analysis of the mesenchymal signature landscape in gliomas.Transcription factor EGR-1 inhibits growth of hepatocellular carcinoma and esophageal carcinoma cell linesEarly growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosisNeural crest cell-autonomous roles of fibronectin in cardiovascular development.Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation.Egr-1 regulates expression of the glial scar component phosphacan in astrocytes after experimental stroke.Mechanoregulation of gene expression in fibroblasts.Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: implications for scleroderma.Increased Expression of EGR-1 in Diabetic Human Adipose Tissue-Derived Mesenchymal Stem Cells Reduces Their Wound Healing Capacity.Gene regulation by mechanotransduction in fibroblasts.Expression profiling of Galectin-3-depleted melanoma cells reveals its major role in melanoma cell plasticity and vasculogenic mimicry.Mislocalized scaffolding by the Na-H exchanger NHE1 dominantly inhibits fibronectin production and TGF-beta activation.Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers.Role of promoter DNA sequence variations on the binding of EGR1 transcription factor.The early-immediate gene EGR-1 is induced by transforming growth factor-beta and mediates stimulation of collagen gene expression.Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1.Identification of H-Ras, RhoA, Rac1 and Cdc42 responsive genes.Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma ) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumorigenic activity.Egr-1 and RNA POL II facilitate glioma cell GDNF transcription induced by histone hyperacetylation in promoter II.FH535 potentiation of cigarette smoke condensate cytotoxicity is associated with changes in β-catenin and EGR-1 signaling.Metastasis suppressor KAI1/CD82 attenuates the matrix adhesion of human prostate cancer cells by suppressing fibronectin expression and β1 integrin activation.The fibrotic phenotype induced by IGFBP-5 is regulated by MAPK activation and egr-1-dependent and -independent mechanisms.Induction of Egr-1 is associated with anti-metastatic and anti-invasive ability of beta-lapachone in human hepatocarcinoma cells.Glycolytic glioma cells with active glycogen synthase are sensitive to PTEN and inhibitors of PI3K and gluconeogenesis.Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation.HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1.
P2860
Q24791972-A4DF63FB-49E9-47D1-BC08-F7187B26EFA5Q30655602-99487969-A026-495B-8B96-032C5CF5EA12Q33214943-D5845F73-5DD8-498A-A482-E710594DD596Q33809324-D030E0BC-14D7-4F35-97D0-FBF49AF1BE13Q34089981-3BD6F72F-AE1D-42A1-8019-05A452D1D809Q34136498-A060AEA0-21B5-498F-9FCB-8BC20365726DQ34468320-FFA78B01-DC27-4020-8F73-13B4BF3BEB1DQ34625392-55D2B606-4EA6-480C-8880-E4006B7D3328Q34867938-3275E9CF-64A3-4495-8DD8-D09A9F256A14Q35158714-95A11029-D8D8-4F1B-ABFD-45A13D2E0BB5Q35575649-7CB54D5C-B178-4ED2-9E82-4A324A608478Q36195011-7073C37C-973B-41EA-BBA6-55AED1148E8CQ36247095-2EBDA915-4DC6-4D0B-B942-E6151C2BE824Q36247578-88E35032-2FEC-4C94-93EE-04218CFB8EFBQ36303247-1740FBF2-8DF4-4F64-9A36-B61510BE3196Q36316031-8A8581E0-ACCB-484B-97B2-6111E502BFBEQ36399732-C28B822E-7395-4C57-B617-028ACDD3C172Q36497251-89A1D40E-429B-42E9-A5C9-E65C6EAB0FD0Q36672324-1352FFD6-5786-490C-A145-683CDE94DBAEQ36734866-873ECFAA-922A-4A98-9B4C-58330E907677Q36748725-A8D6E525-3451-4EFA-BC46-9CF276E499E1Q36891532-B5AFD269-B79E-458C-8A16-8CB168C8533CQ36910723-7B17112C-6AFE-4F6D-96F7-5E618A214122Q37024659-B79A3689-824E-49A1-8000-E454126345FCQ37061114-59389689-0372-405C-A22D-2931A60E257AQ37158427-1B586E00-9A3D-4BFB-B472-D8474105EA2FQ37346035-20BFC46C-CC17-4BF7-B8D7-C091BC4D8000Q37735427-16937663-EFAA-4C9A-BD42-6DFEBF9D60D0Q38313294-60506DDB-9A38-4E78-ADA7-EC619155045CQ38347071-7B206B57-41C0-4555-BD12-6F3B26B0DD6DQ38354961-73661042-22B5-4A70-BCDF-D36BF0DE3E5EQ38359904-6AA9E8C5-469C-4781-B5B8-A655EB8DA047Q38716923-F56BA7D1-1003-47CE-A26A-69A49126249FQ39328449-477964F7-FAB6-456A-8265-DACC43ED176BQ39521054-42D5F530-27DB-4B27-A155-BEC144AB126FQ39821402-8FBE534D-ABA3-4A03-8792-4C30AA6A93A0Q40083030-B5645A9B-4C0B-402B-8135-1C56FF906273Q40371829-477809A6-D43C-4D84-B6DB-4699C514D522Q40433116-74F89C78-E4BC-492F-AD2D-AB79FAD2C986Q40479151-33D516B4-DBAD-46D4-8D9F-2A3D731A7C1E
P2860
The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
The transcription factor EGR-1 ...... n glioblastoma cell line U251.
@en
type
label
The transcription factor EGR-1 ...... n glioblastoma cell line U251.
@en
prefLabel
The transcription factor EGR-1 ...... n glioblastoma cell line U251.
@en
P2093
P2860
P356
P1476
The transcription factor EGR-1 ...... n glioblastoma cell line U251.
@en
P2093
P2860
P304
20315-20323
P356
10.1074/JBC.M909046199
P407
P577
2000-07-01T00:00:00Z