Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE)
about
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cellsCloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cellsTumour necrosis factor alpha converting enzyme (TACE) activity in the colonic mucosa of patients with inflammatory bowel diseaseActivity dependent CAM cleavage and neurotransmissionPhosphatidylserine exposure is required for ADAM17 sheddase functionThe growth hormone receptor interacts with its sheddase, the tumour necrosis factor-alpha-converting enzyme (TACE)The transmembrane domain of TACE regulates protein ectodomain sheddingConstitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzymePhenylbutyric acid rescues endoplasmic reticulum stress-induced suppression of APP proteolysis and prevents apoptosis in neuronal cellsShedding of Collagen XVII/BP180: STRUCTURAL MOTIFS INFLUENCE CLEAVAGE FROM CELL SURFACEDistinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligandsIL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor.The waved with open eyelids (woe) locus is a hypomorphic mouse mutation in Adam17.Ectodomain Shedding by ADAM17: Its Role in Neutrophil Recruitment and the Impairment of This Process during SepsisPhosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.ADAM-17: the enzyme that does it all.Cell-cell interaction promotes rat marrow stromal cell differentiation into endothelial cell via activation of TACE/TNF-alpha signaling.TACE (ADAM17) inhibits Schwann cell myelination.iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier functionConditional inactivation of TACE by a Sox9 promoter leads to osteoporosis and increased granulopoiesis via dysregulation of IL-17 and G-CSF.Intracellular processing of metalloprotease disintegrin ADAM12.Interleukin-1 stimulates ADAM17 through a mechanism independent of its cytoplasmic domain or phosphorylation at threonine 735Unlike for human monocytes after LPS activation, release of TNF-α by THP-1 cells is produced by a TACE catalytically different from constitutive TACE.Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACEiRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPSDirect activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation.Systemic overexpression of TNFα-converting enzyme does not lead to enhanced shedding activity in vivoATP-mediated transactivation of the epidermal growth factor receptor in airway epithelial cells involves DUOX1-dependent oxidation of Src and ADAM17.Conditional inactivation of TNFα-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones.Small therapeutic molecules for the treatment of inflammatory bowel diseaseTACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association.TACE is required for the activation of the EGFR by TGF-alpha in tumorsMigration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17.Epidermal growth factor (EGF) ligand release by substrate-specific a disintegrin and metalloproteases (ADAMs) involves different protein kinase C (PKC) isoenzymes depending on the stimulusFRET-based and other fluorescent proteinase probes.Deletion of Adam10 in endothelial cells leads to defects in organ-specific vascular structures.
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P2860
Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE)
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
@wuu
2000年学术文章
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2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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2000年學術文章
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2000年學術文章
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name
Intracellular maturation and l ...... factor alpha convertase (TACE)
@en
type
label
Intracellular maturation and l ...... factor alpha convertase (TACE)
@en
prefLabel
Intracellular maturation and l ...... factor alpha convertase (TACE)
@en
P2860
P1433
P1476
Intracellular maturation and l ...... factor alpha convertase (TACE)
@en
P2093
C P Blobel
J D Becherer
P2860
P304
P356
10.1042/0264-6021:3470131
10.1042/BJ3470131
P407
P478
P577
2000-04-01T00:00:00Z