Transcriptional regulatory effects of lymphoma-associated NFKB2/lyt10 protooncogenes.
about
Refined physical map of the human PAX2/HOX11/NFKB2 cancer gene region at 10q24 and relocalization of the HPV6AI1 viral integration site to 14q13.3-q21.1Myc suppression of Nfkb2 accelerates lymphomagenesis.MEOX2 regulates nuclear factor-kappaB activity in vascular endothelial cells through interactions with p65 and IkappaBbetaFunctions of NF-kappaB1 and NF-kappaB2 in immune cell biologyConstitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cellsTNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.Constitutive production of NF-kappaB2 p52 is not tumorigenic but predisposes mice to inflammatory autoimmune disease by repressing Bim expression.NF-kappa B2 p100 is a pro-apoptotic protein with anti-oncogenic function.Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.
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P2860
Transcriptional regulatory effects of lymphoma-associated NFKB2/lyt10 protooncogenes.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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2000年學術文章
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2000年學術文章
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name
Transcriptional regulatory effects of lymphoma-associated NFKB2/lyt10 protooncogenes.
@en
type
label
Transcriptional regulatory effects of lymphoma-associated NFKB2/lyt10 protooncogenes.
@en
prefLabel
Transcriptional regulatory effects of lymphoma-associated NFKB2/lyt10 protooncogenes.
@en
P2093
P2860
P356
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Transcriptional regulatory effects of lymphoma-associated NFKB2/lyt10 protooncogenes.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203432
P407
P577
2000-03-01T00:00:00Z
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P6179
1032510678