Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.
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SWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcriptionTranscription activator interactions with multiple SWI/SNF subunits.Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signalingDisruption of Ini1 leads to peri-implantation lethality and tumorigenesis in miceHuman rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.Chapter 5. Nuclear actin-related proteins in epigenetic control.Mutation analysis of human cytokeratin 8 gene in malignant rhabdoid tumor: a possible association with intracytoplasmic inclusion body formation.Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors.Ubiquitin-dependent and ubiquitin-independent control of subunit stoichiometry in the SWI/SNF complex.The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumorsBRG-1 is required for RB-mediated cell cycle arrestSNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development.The histone methyltransferase SUV39H1 suppresses embryonal rhabdomyosarcoma formation in zebrafish.BRG1 controls the activity of the retinoblastoma protein via regulation of p21CIP1/WAF1/SDI.Are gene expression microarray analyses reliable? A review of studies of retinoic acid responsive genesAdult human sarcomas. I. Basic science.Adult human sarcomas. II. Medical oncology.MYC interaction with the tumor suppressive SWI/SNF complex member INI1 regulates transcription and cellular transformation.Embryonal central nervous system neoplasms arising in infants and young children: a pediatric brain tumor consortium studyA comparative genomic approach for identifying synthetic lethal interactions in human cancer.The role of INI1/hSNF5 in gene regulation and cancer.Hijacking the chromatin remodeling machinery: impact of SWI/SNF perturbations in cancer.Deregulated chromatin remodeling in the pathobiology of brain tumors.Epigenomic regulation of oncogenesis by chromatin remodeling.Failure to downregulate the BAF53a subunit of the SWI/SNF chromatin remodeling complex contributes to the differentiation block in rhabdomyosarcoma.Dependence on PI3K/Akt signaling for malignant rhabdoid tumor cell survivalThe Brm gene suppressed at the post-transcriptional level in various human cell lines is inducible by transient HDAC inhibitor treatment, which exhibits antioncogenic potential.Transcriptional co-activator activity of SYT is negatively regulated by BRM and Brg1.The BRG-1 subunit of the SWI/SNF complex regulates CD44 expression.The myogenic basic helix-loop-helix family of transcription factors shows similar requirements for SWI/SNF chromatin remodeling enzymes during muscle differentiation in culture.Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB.A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle.Derivative chromosome 9 deletions in chronic myeloid leukemia are associated with loss of tumor suppressor genes.Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations.Human medulloblastomas lack point mutations and homozygous deletions of the hSNF5/INI1 tumour suppressor gene.Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: differential effects on RB-mediated growth arrest vs CD44 expression.Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis
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P2860
Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Alteration of hSNF5/INI1/BAF47 ...... arcomas but not Wilms' tumors.
@en
type
label
Alteration of hSNF5/INI1/BAF47 ...... arcomas but not Wilms' tumors.
@en
prefLabel
Alteration of hSNF5/INI1/BAF47 ...... arcomas but not Wilms' tumors.
@en
P2093
P2860
P4510
P356
P1433
P1476
Alteration of hSNF5/INI1/BAF47 ...... arcomas but not Wilms' tumors.
@en
P2093
B E Weissman
M F DeCristofaro
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203168
P407
P577
1999-12-01T00:00:00Z
P5875
P6179
1004922334