Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line.
about
Mathematical model of metabolism and electrophysiology of amino acid and glucose stimulated insulin secretion: in vitro validation using a β-cell lineTransfection of rat pancreatic islet tissue by polymeric gene vectors.Physiological and pharmacological regulation of insulin release: insights offered through exploitation of insulin-secreting cell lines.Amino acid transporters: roles in amino acid sensing and signalling in animal cells.Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice.Increased amino acid supply potentiates glucose-stimulated insulin secretion but does not increase β-cell mass in fetal sheep.Dose- and Glucose-Dependent Effects of Amino Acids on Insulin Secretion from Isolated Mouse Islets and Clonal INS-1E Beta-Cells.A highly energetic process couples calcium influx through L-type calcium channels to insulin secretion in pancreatic beta-cells.Insulinotropic and muscle protein synthetic effects of branched-chain amino acids: potential therapy for type 2 diabetes and sarcopenia.Amino acid-induced gene expression profiling in clonal β-cell line INS-1E cells.Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic β-cell dysfunction.Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism.Pre-incubation with interleukin-4 mediates a direct protective effect against the loss of pancreatic beta-cell viability induced by proinflammatory cytokines.Effect of cytochalasin B on 3-O-[(14)C]-methyl-D-glucose or D-[U-(14)C]glucose handling by BRIN-BD11 cells.Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide.The dynamic plasticity of insulin production in β-cells.Branched-chain amino acid supplementation restores reduced insulinotropic activity of a low-protein diet through the vagus nerve in rats.Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice.Arginine induces GH gene expression by activating NOS/NO signaling in rat isolated hemi-pituitaries.Effects of chronic exposure of clonal β-cells to elevated glucose and free fatty acids on incretin receptor gene expression and secretory responses to GIP and GLP-1.A novel peptide Phylloseptin-PBu from Phyllomedusa burmeisteri possesses insulinotropic activity via potassium channel and GLP-1 receptor signalling.L-serine supplementation lowers diabetes incidence and improves blood glucose homeostasis in NOD mice.
P2860
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P2860
Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Mechanisms of amino acid-induc ...... N-BD11 pancreatic B-cell line.
@en
type
label
Mechanisms of amino acid-induc ...... N-BD11 pancreatic B-cell line.
@en
prefLabel
Mechanisms of amino acid-induc ...... N-BD11 pancreatic B-cell line.
@en
P2093
P921
P356
P1476
Mechanisms of amino acid-induc ...... IN-BD11 pancreatic B-cell line
@en
P2093
C R Barnett
N H McClenaghan
P304
P356
10.1677/JOE.0.1510349
P407
P50
P577
1996-12-01T00:00:00Z