A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture.
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Correction of the disease phenotype in the mouse model of Stargardt disease by lentiviral gene therapyViolet and blue light blocking intraocular lenses: photoprotection versus photoreceptionThe Photobiology of Lutein and Zeaxanthin in the EyeRetinol Dehydrogenases Regulate Vitamin A Metabolism for Visual FunctionRetinal pigment epithelium defects in humans and mice with mutations in MYO7A: imaging melanosome-specific autofluorescence.Cone photoreceptor abnormalities correlate with vision loss in patients with Stargardt disease.A novel source of methylglyoxal and glyoxal in retina: implications for age-related macular degenerationImmunochemical recognition of A2E, a pigment in the lipofuscin of retinal pigment epithelial cells.Phospholipid meets all-trans-retinal: the making of RPE bisretinoidsPhotooxidation of RPE lipofuscin bisretinoids enhances fluorescence intensity.The value of measurement of macular carotenoid pigment optical densities and distributions in age-related macular degeneration and other retinal disordersUltra-widefield fundus autofluorescence in age-related macular degeneration.Oxidative stress and histological changes in a model of retinal phototoxicity in rabbitsAccelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementationSynthesis of antioxidants for prevention of age-related macular degenerationFormation of lipofuscin-like material in the RPE Cell by different components of rod outer segments.Fundus autofluorescence and the bisretinoids of retina.Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate.Effects of organic solvents on two retinal pigment epithelial lipofuscin fluorophores, A2E and all-trans-retinal dimerRetinoids for treatment of retinal diseasesBiosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degenerationAltered retinoid homeostasis catalyzed by a nicotine metabolite: implications in macular degeneration and normal developmentEndogenous fluorophores enable two-photon imaging of the primate eye.Enzymatic degradation of A2E, a retinal pigment epithelial lipofuscin bisretinoid.The retinal pigment epithelium in health and diseaseVitamin A dimers trigger the protracted death of retinal pigment epithelium cellsThe lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium.Comparison of A2E cytotoxicity and phototoxicity with all-trans-retinal in human retinal pigment epithelial cellsPharmacological inhibition of lipofuscin accumulation in the retina as a therapeutic strategy for dry AMD treatment.Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease.Design, synthesis, and evaluation of nonretinoid retinol binding protein 4 antagonists for the potential treatment of atrophic age-related macular degeneration and Stargardt disease.High resolution MALDI imaging mass spectrometry of retinal tissue lipids.Anthocyanins protect against A2E photooxidation and membrane permeabilization in retinal pigment epithelial cellsFundus autofluorescence findings in a mouse model of retinal detachment.Mass spectrometry provides accurate and sensitive quantitation of A2E.Deuterium enrichment of vitamin A at the C20 position slows the formation of detrimental vitamin A dimers in wild-type rodentsNoninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes.Spectroscopic and morphological studies of human retinal lipofuscin granules.Therapy for macular degeneration: insights from acnePhototoxic action spectrum on a retinal pigment epithelium model of age-related macular degeneration exposed to sunlight normalized conditions
P2860
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P2860
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture.
@en
type
label
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture.
@en
prefLabel
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture.
@en
P2093
P1476
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture
@en
P2093
Hashimoto M
Nakanishi K
Sparrow JR
P304
P407
P577
1999-11-01T00:00:00Z