Lentivirus-mediated Bcl-2 expression in betaTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion.
about
Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokinesPartial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions.Lentivectors encoding immunosuppressive proteins genetically engineer pancreatic beta-cells to correct diabetes in allogeneic mice.Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosisNew therapeutic approaches to type 1 diabetes: from prevention to cellular or gene therapies.Gene- and cell-based therapeutics for type I diabetes mellitus.Clic4, a novel protein that sensitizes β-cells to apoptosisGluco-incretins regulate beta-cell glucose competence by epigenetic silencing of Fxyd3 expressionNonhuman primate models in type 1 diabetes research.XIAP overexpression in islet beta-cells enhances engraftment and minimizes hypoxia-reperfusion injury.Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells.Treatment of diabetic rats with encapsulated islets.Induction of beta-cell resistance to hypoxia and technologies for oxygen delivery to transplanted pancreatic islets.High-density lipoprotein, beta cells, and diabetes .Dual factor delivery of CXCL12 and Exendin-4 for improved survival and function of encapsulated beta cells under hypoxic conditions.Tetracycline-regulated expression of VEGF-A in beta cells induces angiogenesis: improvement of engraftment following transplantation.Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion.Retrovirally transferred genes inhibit apoptosis in an insulin-secreting cell line: implications for islet transplantation.Destruction of conditional insulinoma cell lines in NOD mice: a role for autoimmunity.SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma.Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma -mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells.MRI-detectable pH nanosensors incorporated into hydrogels for in vivo sensing of transplanted-cell viability.Bcl-2 and Bcl-xL suppress glucose signaling in pancreatic β-cellsGenetically modified adenovirus vector containing an RGD peptide in the HI loop of the fiber knob improves gene transfer to nonhuman primate isolated pancreatic islets.Identification of iduronate-2-sulfatase in mouse pancreatic islets.Lentivirus-mediated gene transfer of viral interleukin-10 delays but does not prevent cardiac allograft rejection.
P2860
Q28568056-456CB958-F819-4B51-AE85-42805D5A0817Q28941780-DBAC0650-6DF9-4ADD-94BB-4125CC57413AQ33980424-2B025EAA-8EC2-4F57-9D94-E77F16A80014Q34344718-CE0F7C26-CE07-4BA5-8882-C2CBDFCBD793Q34564255-B2D68AEF-31C9-4F8B-B331-B9B1270B11E4Q35122170-5CDA45F8-3A07-4AC8-8196-46CA93BFE6EBQ35163097-495F2FC9-DED5-47F5-A7BC-37A52AC1DE85Q35212540-787D64A7-8022-419F-9E1D-66011876EFCBQ35823996-54B7552D-C8FF-4CD1-BD2A-806BFD43D5F4Q36124141-BBCF0E30-EED6-467F-845D-BB6583A34EE9Q37267118-1DD134CD-987E-46AF-91BF-CA4BEB5A0C6CQ37310687-F0DBCBC7-3C7A-492C-A6D2-62CE183CCC7BQ37990469-CD4591DE-C0B8-4FD8-B43B-8621C60CEA59Q38218039-B85056E8-FD37-4505-862C-DB1F170F57CCQ39189393-2ED6F079-8A1B-4CC0-BE98-AD2F90B251C6Q40193843-55F19011-5CFE-4D43-86BA-D4E8B6CD4C21Q40392908-FB002851-6D0A-4FEF-8E1A-333A538683B2Q40487706-FA444AD0-72B7-4C10-A94D-1D288935A329Q40648865-488B36AA-8B96-4587-B56D-9E3921FDDA29Q40807388-03B20FED-2B23-429D-88B4-B483C599FF3AQ40857756-E1A6CC6A-C400-40B2-BF1B-CC9B2B5D8FE8Q42006889-FF256B3A-1D06-4E30-887C-4099F728067BQ42168256-CB93BA31-7B25-44CA-B150-A0189CE8DC92Q44049643-8716FE7C-0DE4-44C4-A6F4-1864182D04F0Q44901006-7E506D32-4ED0-48EB-BCD1-180162C2A4E8Q45883107-7ED0823B-AF65-43B2-868C-D18D392E5B9E
P2860
Lentivirus-mediated Bcl-2 expression in betaTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Lentivirus-mediated Bcl-2 expr ...... control of insulin secretion.
@en
type
label
Lentivirus-mediated Bcl-2 expr ...... control of insulin secretion.
@en
prefLabel
Lentivirus-mediated Bcl-2 expr ...... control of insulin secretion.
@en
P2093
P2860
P356
P1433
P1476
Lentivirus-mediated Bcl-2 expr ...... control of insulin secretion.
@en
P2093
Pralong WF
Zufferey R
P2860
P2888
P304
P356
10.1038/SJ.GT.3300922
P577
1999-06-01T00:00:00Z
P5875
P6179
1050155587