The type 2 diabetes-associated gene ide is required for insulin secretion and suppression of α-synuclein levels in β-cells.
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Mechanisms of Aβ Clearance and Degradation by Glial CellsAmylin at the interface between metabolic and neurodegenerative disordersBridging Type 2 Diabetes and Alzheimer's Disease: Assembling the Puzzle Pieces in the Quest for the Molecules With Therapeutic and Preventive PotentialUnraveling Alzheimer's: Making Sense of the Relationship between Diabetes and Alzheimer's Disease1MicroRNA-7a regulates pancreatic β cell function.Type 2 diabetes as a protein misfolding disease.Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo.Altered Plasma Profile of Antioxidant Proteins as an Early Correlate of Pancreatic β Cell Dysfunction.Cross-talk between amyloidogenic proteins in type-2 diabetes and Parkinson's disease.Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses.The diabetes gene Hhex maintains δ-cell differentiation and islet function.Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes.Minireview: Autophagy in pancreatic β-cells and its implication in diabetes.Targeting Insulin-Degrading Enzyme to Treat Type 2 Diabetes MellitusCandidate gene analysis supports a role for polymorphisms at TCF7L2 as risk factors for type 2 diabetes in Sudan.Potential efficacy of Lactobacillus casei IBRC_M10711 on expression and activity of insulin degrading enzyme but not insulin degradation.Insulin-degrading enzyme: new therapeutic target for diabetes and Alzheimer's disease?Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy.Prion-Like Protein Aggregates and Type 2 Diabetes.Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to endosomes.Insulin-degrading enzyme inhibition, a novel therapy for type 2 diabetes?Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner.Extracellular vesicles from human pancreatic islets suppress human islet amyloid polypeptide amyloid formation.Diet-induced obesity accelerates the onset of terminal phenotypes in α-synuclein transgenic mice.Multiple functions of insulin-degrading enzyme: a metabolic crosslight?The cell biology of systemic insulin function.Reduced insulin clearance and lower insulin-degrading enzyme expression in the liver might contribute to the thrifty phenotype of protein-restricted mice.Hematopoietically expressed homeobox gene is associated with type 2 diabetes in KK Cg-Ay/J mice and a Taiwanese Han Chinese population.
P2860
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P2860
The type 2 diabetes-associated gene ide is required for insulin secretion and suppression of α-synuclein levels in β-cells.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The type 2 diabetes-associated ...... α-synuclein levels in β-cells.
@en
type
label
The type 2 diabetes-associated ...... α-synuclein levels in β-cells.
@en
prefLabel
The type 2 diabetes-associated ...... α-synuclein levels in β-cells.
@en
P2093
P2860
P356
P1433
P1476
The type 2 diabetes-associated ...... α-synuclein levels in β-cells.
@en
P2093
Claes-Göran Ostenson
Fredrik Backlund
Lisa Lundberg
Lisandro Bernardo
Pär Steneberg
Sara Edfalk
P2860
P304
P356
10.2337/DB12-1045
P407
P577
2013-01-24T00:00:00Z