GABA signaling stimulates α-cell-mediated β-like cell neogenesis

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GABA signaling stimulates α-cell-mediated β-like cell neogenesis

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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GABA signaling stimulates α-cell-mediated β-like cell neogenesis

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GABA signaling stimulates α-cell-mediated β-like cell neogenesis

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GABA signaling stimulates α-cell-mediated β-like cell neogenesis

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P1476

GABA signaling stimulates α-cell-mediated β-like cell neogenesis

@en

P2093

Ahmed Mansouri

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Andhira Vieira

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Biljana Hadzic

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Elisabet Gjernes

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Monica Courtney

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Nouha Ben-Othman

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Noémie Druelle

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Patrick Collombat

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Serena Silvano

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Sergi Navarro Sanz

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P2860

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells

Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

Modulation of GABAA receptor activity by phosphorylation and receptor trafficking: implications for the efficacy of synaptic inhibition.

GABA in the endocrine pancreas: its putative role as an islet cell paracrine-signalling molecule.

Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression.

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities.

P304

e1300215

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P31

scholarly article

P356

10.1080/19420889.2017.1300215

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Fabio Avolio

P577

2017-03-02T00:00:00Z

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P698

28702122

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P932

5501192

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