Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells.
about
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identitiesPairing of homologous regions in the mouse genome is associated with transcription but not imprinting statusSingle-strand recombination signal sequence nicks in vivo: evidence for a capture model of synapsisRAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin lociYY1 controls Igκ repertoire and B-cell development, and localizes with condensin on the Igκ locusIndependent recruitment of Igh alleles in V(D)J recombination.Decreased replication origin activity in temporal transition regionsLoss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells.Epigenetic control of immunityThe mouse immunoglobulin heavy chain V-D intergenic sequence contains insulators that may regulate ordered V(D)J recombinationHierarchies in eukaryotic genome organization: Insights from polymer theory and simulations.Chromatin dynamics.Epigenetic control of recombination in the immune systemRegulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitmentNuclear RNA sequencing of the mouse erythroid cell transcriptomeVisceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development.ATM influences the efficiency of TCRβ rearrangement, subsequent TCRβ-dependent T cell development, and generation of the pre-selection TCRβ CDR3 repertoire.Transcription and recombination factories: common features?Mechanism and regulation of class switch recombinationThe center of accessibility: Dβ control of V(D)J recombinationA multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location.RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation.CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cellsCis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production.Pre-B cell receptor signaling induces immunoglobulin κ locus accessibility by functional redistribution of enhancer-mediated chromatin interactions.Epigenetic histone modifications do not control Igkappa locus contraction and intranuclear localization in cells with dual B cell-macrophage potential.IL-7R expression and IL-7 signaling confer a distinct phenotype on developing human B-lineage cells.Yin Yang 1 is a critical regulator of B-cell developmentAntisense intergenic transcription precedes Igh D-to-J recombination and is controlled by the intronic enhancer Emu.CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability.A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformationNoncommutative Biology: Sequential Regulation of Complex Networks.Mechanisms of Yin Yang 1 in oncogenesis: the importance of indirect effects.Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci.Chromosomal position of a VH gene segment determines its activation and inactivation as a substrate for V(D)J recombination.Chromatin loops, gene positioning, and gene expression.Noncoding transcription within the Igh distal V(H) region at PAIR elements affects the 3D structure of the Igh locus in pro-B cellsTurning T-cell receptor beta recombination on and off: more questions than answers.E47 is required for V(D)J recombinase activity in common lymphoid progenitors.
P2860
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P2860
Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Visualization of looping invol ...... n locus in developing B cells.
@en
type
label
Visualization of looping invol ...... n locus in developing B cells.
@en
prefLabel
Visualization of looping invol ...... n locus in developing B cells.
@en
P2093
P2860
P356
P1433
P1476
Visualization of looping invol ...... n locus in developing B cells.
@en
P2093
Camil E Sayegh
Cornelis Murre
Roy Riblet
Suchit Jhunjhunwala
P2860
P304
P356
10.1101/GAD.1254305
P577
2005-02-01T00:00:00Z