Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype.
about
Human telomerase and its regulationCrisis intervention: the role of telomeraseAcquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expressionMutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathiesReplacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responsesComplex roles for telomeres and telomerase in breast carcinogenesisGeneration of bovine transgenics using somatic cell nuclear transferSpecific genetic modifications of domestic animals by gene targeting and animal cloningCreation of non-human primate neurogenetic disease models by gene targeting and nuclear transferTelomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G1 checkpoint function.Strict control of telomerase activation using Cre-mediated inversion.Therapeutic Targeting of TelomeraseTelomeres and telomerase as therapeutic targets to prevent and treat age-related diseasesIn Vitro Cell Models for Ophthalmic Drug Development ApplicationsImmortalization of Primary Keratinocytes and Its Application to Skin ResearchThe Importance of Physiologically Relevant Cell Lines for Studying Virus-Host InteractionsMolecular characterization and developmental expression of NORPEG, a novel gene induced by retinoic acidDendritic cells reconstituted with human telomerase gene induce potent cytotoxic T-cell response against different types of tumorsHuman growth hormone-regulated HOXA1 is a human mammary epithelial oncogeneIncreased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cellsSimultaneous visualization of both signaling cascade activity and end-point gene expression in single cellsObatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection.Cell division and cell survival in the absence of survivin.PKN binds and phosphorylates human papillomavirus E6 oncoprotein.Natural and pharmacological regulation of telomeraseTelomerized presenescent osteoblasts prevent bone mass loss in vivo.Isolation and characterization of a spontaneously immortalized bovine retinal pigmented epithelial cell line.Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis.Alzheimer Abeta peptide induces chromosome mis-segregation and aneuploidy, including trisomy 21: requirement for tau and APP.Role of telomerase in cellular proliferation and cancer.hTERT-Immortalized Bone Mesenchymal Stromal Cells Expressing Rat Galanin via a Single Tetracycline-Inducible Lentivirus SystemRestoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres.Alternative pathways for the extension of cellular life span: inactivation of p53/pRb and expression of telomerase.The role of senescence and immortalization in carcinogenesis.Switching of mesodermal and endodermal properties in hTERT-modified and expanded fetal human pancreatic progenitor cells.Disease states associated with telomerase deficiency appear earlier in mice with short telomeresFlow cytometric measurement of telomere length.Constitutive telomerase expression promotes mammary carcinomas in aging mice.
P2860
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P2860
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Telomerase expression in human ...... with a transformed phenotype.
@en
type
label
Telomerase expression in human ...... with a transformed phenotype.
@en
prefLabel
Telomerase expression in human ...... with a transformed phenotype.
@en
P2093
P356
P1433
P1476
Telomerase expression in human ...... with a transformed phenotype.
@en
P2093
A G Bodnar
P304
P356
10.1038/5056
P407
P577
1999-01-01T00:00:00Z
P5875
P6179
1025196806