A functional virulence complex composed of gingipains, adhesins, and lipopolysaccharide shows high affinity to host cells and matrix proteins and escapes recognition by host immune systems.
about
The outer membrane protein LptO is essential for the O-deacylation of LPS and the co-ordinated secretion and attachment of A-LPS and CTD proteins in Porphyromonas gingivalis.Expression of Arg-Gingipain RgpB is required for correct glycosylation and stability of monomeric Arg-gingipain RgpA from Porphyromonas gingivalis W50.A Porphyromonas gingivalis mutant defective in a putative glycosyltransferase exhibits defective biosynthesis of the polysaccharide portions of lipopolysaccharide, decreased gingipain activities, strong autoaggregation, and increased biofilm formatiDichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins.Clathrin-dependent entry of a gingipain adhesin peptide and Porphyromonas gingivalis into host cellsDisruption of the endothelial barrier by proteases from the bacterial pathogen Pseudomonas aeruginosa: implication of matrilysis and receptor cleavageInhibition of human immunodeficiency virus type 1 entry by a binding domain of Porphyromonas gingivalis gingipainProtective and destructive immunity in the periodontium: Part 1--innate and humoral immunity and the periodontium.Protective and destructive immunity in the periodontium: Part 2--T-cell-mediated immunity in the periodontium.Involvement of an Skp-Like Protein, PGN_0300, in the Type IX Secretion System of Porphyromonas gingivalis.The interaction of bacterial pathogens with platelets.Porphyromonas gingivalis: keeping the pathos out of the biont.Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalisThe gingipains: scissors and glue of the periodontal pathogen, Porphyromonas gingivalis.Protein selection and export via outer membrane vesicles.Gingipains from Porphyromonas gingivalis - Complex domain structures confer diverse functionsAttenuation of the phosphatidylinositol 3-kinase/Akt signaling pathway by Porphyromonas gingivalis gingipains RgpA, RgpB, and Kgp.Cleavage of protease-activated receptors on an immortalized oral epithelial cell line by Porphyromonas gingivalis gingipains.The effect of butyric acid on adhesion molecule expression by human gingival epithelial cells.Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases.Interleukin-1alpha stimulation in monocytes by periodontal bacteria: antagonistic effects of Porphyromonas gingivalis.Gingipains inactivate a cell surface ligand on Porphyromonas gingivalis that induces TLR2-and TLR4-independent signaling.The Porphyromonas gingivalis O antigen is required for inhibition of apoptosis in gingival epithelial cells following bacterial infection.Fibroblast apoptosis induced by Porphyromonas gingivalis is stimulated by a gingipain and caspase-independent pathway that involves apoptosis-inducing factor.Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'-phosphatase activities.Role for gingipains in Porphyromonas gingivalis traffic to phagolysosomes and survival in human aortic endothelial cells.Molecular mechanisms of Porphyromonas gingivalis-host cell interaction on periodontal diseases.Further evidence that major outer membrane proteins homologous to OmpA in Porphyromonas gingivalis stabilize bacterial cells.
P2860
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P2860
A functional virulence complex composed of gingipains, adhesins, and lipopolysaccharide shows high affinity to host cells and matrix proteins and escapes recognition by host immune systems.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
A functional virulence complex ...... nition by host immune systems.
@en
type
label
A functional virulence complex ...... nition by host immune systems.
@en
prefLabel
A functional virulence complex ...... nition by host immune systems.
@en
P2093
P2860
P1476
A functional virulence complex ...... nition by host immune systems.
@en
P2093
Atsuyo Baba
Kenji Yamamoto
Ryosuke Takii
Takayuki Tsukuba
Tomoko Kadowaki
P2860
P304
P356
10.1128/IAI.73.2.883-893.2005
P407
P577
2005-02-01T00:00:00Z