Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain.
about
Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53p53 Stabilization and accumulation induced by human vaccinia-related kinase 1The N-terminal interferon-binding domain (IBiD) homology domain of p300 binds to peptides with homology to the p53 transactivation domain.HDM2 negatively affects the Chk2-mediated phosphorylation of p53.A novel p53 phosphorylation site within the MDM2 ubiquitination signal: I. phosphorylation at SER269 in vivo is linked to inactivation of p53 function.Bioinformatics study of cancer-related mutations within p53 phosphorylation site motifsAssessing G1-to-S-phase progression after genotoxic stress.DNA damage-induced cell death: lessons from the central nervous system.What's new in p53?p53: the attractive tumor suppressor in the cancer research field.Role of p53 in Cell Death and Human Cancers.The regulation of p53 by phosphorylation: a model for how distinct signals integrate into the p53 pathway.A central role for CK1 in catalyzing phosphorylation of the p53 transactivation domain at serine 20 after HHV-6B viral infection.Stability of checkpoint kinase 2 is regulated via phosphorylation at serine 456.The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members.Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage.ATM-dependent CHK2 activation induced by anticancer agent, irofulven.DNA-dependent protein kinase and checkpoint kinase 2 synergistically activate a latent population of p53 upon DNA damage.Activation of the DNA-binding ability of latent p53 protein by protein kinase C is abolished by protein kinase CK2.Induction of p53 Phosphorylation at Serine 20 by Resveratrol Is Required to Activate p53 Target Genes, Restoring Apoptosis in MCF-7 Cells Resistant to Cisplatin
P2860
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P2860
Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain.
@en
type
label
Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain.
@en
prefLabel
Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain.
@en
P2093
P2860
P1433
P1476
Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain
@en
P2093
Ashley Craig
Graeme Smith
Kathryn Ball
Lindsay Burch
P2860
P304
P356
10.1038/SJ.EMBOR.EMBOR901
P50
P577
2003-08-01T00:00:00Z