Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B.
about
Two adjacent domains (141-150 and 151-160) of apoE covalently linked to a class A amphipathic helical peptide exhibit opposite atherogenic effects.The helix bundle: a reversible lipid binding motifAnti-inflammatory and recycling properties of an apolipoprotein mimetic peptide, Ac-hE18A-NH(2)Type III hyperlipoproteinemic phenotype in transgenic mice expressing dysfunctional apolipoprotein E.Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice.Intestinal expression of human apolipoprotein A-IV in transgenic mice fails to influence dietary lipid absorption or feeding behavior.Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall.Oral administration of L-mR18L, a single domain cationic amphipathic helical peptide, inhibits lesion formation in ApoE null mice.Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null miceTransgenic mouse models of lipoprotein metabolism and atherosclerosisRemnant-like lipoprotein particles impair endothelial function: direct and indirect effects on nitric oxide synthase.Modification by acrolein, a component of tobacco smoke and age-related oxidative stress, mediates functional impairment of human apolipoprotein E.Triptolide inhibits the progression of atherosclerosis in apolipoprotein E-/- mice.An apolipoprotein E synthetic peptide targets to lipoproteins in plasma and mediates both cellular lipoprotein interactions in vitro and acute clearance of cholesterol-rich lipoproteins in vivo.Cholesterol lowering in low density lipoprotein receptor knockout mice overexpressing apolipoprotein E.Apolipoprotein E mimetics and cholesterol-lowering properties.Aberrant expression of neutrophil and macrophage-related genes in a murine model for human neutrophil-specific granule deficiency.Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic miceThe significance of apolipoprotein E structure to the metabolism of plasma triglyceride-rich lipoproteins.Orientation and mode of lipid-binding interaction of human apolipoprotein E C-terminal domain.Effect of protamine on lipoprotein lipase and hepatic lipase in rats.Modulation of the lipid binding properties of the N-terminal domain of human apolipoprotein E3.Overexpression of lipoprotein lipase in transgenic rabbits inhibits diet-induced hypercholesterolemia and atherosclerosis.Lipid-bound structure of an apolipoprotein E-derived peptide.Helix orientation of the functional domains in apolipoprotein e in discoidal high density lipoprotein particles.Examination of lipid-bound conformation of apolipoprotein E4 by pyrene excimer fluorescence.Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by intramuscular injection of plasmid DNA.Hepatic lipid accumulation in apolipoprotein C-I-deficient mice is potentiated by cholesteryl ester transfer protein.
P2860
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P2860
Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Plasma lipoprotein metabolism ...... s containing apolipoprotein B.
@en
type
label
Plasma lipoprotein metabolism ...... s containing apolipoprotein B.
@en
prefLabel
Plasma lipoprotein metabolism ...... s containing apolipoprotein B.
@en
P2093
P2860
P356
P1476
Plasma lipoprotein metabolism ...... s containing apolipoprotein B.
@en
P2093
Yamamoto K
P2860
P304
P356
10.1172/JCI116091
P407
P577
1992-11-01T00:00:00Z