Correlation between oral drug absorption in humans, and apparent drug permeability in TC-7 cells, a human epithelial intestinal cell line: comparison with the parental Caco-2 cell line.
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TEER measurement techniques for in vitro barrier model systemsPrediction of the permeability of neutral drugs inferred from their solvation propertiesA biocompatible micro cell culture chamber (microCCC) for the culturing and on-line monitoring of eukaryote cells.Vorinostat-like molecules as structural, stereochemical, and pharmacological toolsMetabolites of amygdalin under simulated human digestive fluids.High-affinity σ1 protein agonist reduces clinical and pathological signs of experimental autoimmune encephalomyelitis.2,3-Dihydro-1-benzofuran derivatives as a series of potent selective cannabinoid receptor 2 agonists: design, synthesis, and binding mode prediction through ligand-steered modeling.Effects of silver nanoparticles and ions on a co-culture model for the gastrointestinal epitheliumDevelopment and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies.Drug-transporter mediated interactions between anthelminthic and antiretroviral drugs across the Caco-2 cell monolayers.Caco-2 cell permeability assays to measure drug absorption.Selection of a trioxaquine as an antimalarial drug candidate.Importance of disrupted intestinal barrier in inflammatory bowel diseases.Cell-based in vitro models for predicting drug permeability.Drug discovery and regulatory considerations for improving in silico and in vitro predictions that use Caco-2 as a surrogate for human intestinal permeability measurements.Do Caco-2 subclones provide more appropriate in vitro models for understanding how human enteric pathogens cause disease?Dose-dependent targeted suppression of P-glycoprotein expression and function in Caco-2 cellsNatural resistance to apoptosis correlates with resistance to chemotherapy in colorectal cancer cells.Computational approaches for modeling human intestinal absorption and permeability.Orally available Mn porphyrins with superoxide dismutase and catalase activities.Plant polyphenols and multidrug resistance: effects of dietary flavonoids on drug transporters in Caco-2 and MDCKII-MDR1 cell transport models.Self-assembled α-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier.A bacterial encoded protein induces extreme multinucleation and cell-cell internalization in intestinal cells.A cell-based molecular transport simulator for pharmacokinetic prediction and cheminformatic exploration.Lutein transport by Caco-2 TC-7 cells occurs partly by a facilitated process involving the scavenger receptor class B type I (SR-BI).Caco-2 cells as a model for intestinal absorption.Mass transfer and nutrient absorption in a simulated model of small intestine.Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines.In vitro assessment of intestinal permeability and hepatic metabolism of 4'-bromoflavone, a promising cancer chemopreventive agent.Preclinical pharmacokinetic characterization of 2-(4-(4-(5-(2-phenyl-5-(trifluoromethyl)oxazole-4-carboxamido)-1H-benzo[d]imidazol-2-yl)phenyl)cyclohexyl) acetic acid, a novel DGAT-1 inhibitor.Chromium nanoparticle exhibits higher absorption efficiency than chromium picolinate and chromium chloride in Caco-2 cell monolayers.Kinetic modelling of passive transport and active efflux of a fluoroquinolone across Caco-2 cells using a compartmental approach in NONMEM.Human topoisomerase inhibition and DNA/BSA binding of Ru(II)-SCAR complexes as potential anticancer candidates for oral application.Bioavailability of hop-derived iso-α-acids and reduced derivatives.Effect of chitosan-coated alginate microspheres on the permeability of Caco-2 cell monolayers.Synthesis and characterization of chitosan-grafted-polycaprolactone micelles for modulate intestinal paclitaxel delivery.Role of P-glycoprotein in the uptake/efflux transport of oral vitamin K antagonists and rivaroxaban through the Caco-2 cell model.Absorption of dimethoxycinnamic acid derivatives in vitro and pharmacokinetic profile in human plasma following coffee consumption.Formulation design of oral pediatric Acetazolamide suspension: dose uniformity and physico-chemical stability study.Pharmacokinetic characterization of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone, a novel 11β-hydroxysteroid dehydrogenase type 1 inhibitor in rats.
P2860
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P2860
Correlation between oral drug absorption in humans, and apparent drug permeability in TC-7 cells, a human epithelial intestinal cell line: comparison with the parental Caco-2 cell line.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Correlation between oral drug ...... the parental Caco-2 cell line.
@en
type
label
Correlation between oral drug ...... the parental Caco-2 cell line.
@en
prefLabel
Correlation between oral drug ...... the parental Caco-2 cell line.
@en
P2093
P356
P1476
Correlation between oral drug ...... the parental Caco-2 cell line.
@en
P2093
P304
P356
10.1023/A:1011919003030
P577
1998-05-01T00:00:00Z