Three amino acids in the C-linker are major determinants of gating in cyclic nucleotide-gated channels.
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Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMPStructural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channelLigand sensitivity of the 2 subunit from the bovine cone cGMP-gated channel is modulated by protein kinase C but not by calmodulinC-Linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gatingCyclic nucleotide-gated channels. Molecular mechanisms of activation.The carboxyl-terminal region of cyclic nucleotide-modulated channels is a gating ring, not a permeation path.Molecular determinants of KATP channel inhibition by ATP.Oxidative modulation of voltage-gated potassium channels."Light" reading: targeting tryptophans in cyclic nucleotide-gated channelsMovement of gating machinery during the activation of rod cyclic nucleotide-gated channels.Mutating three residues in the bovine rod cyclic nucleotide-activated channel can switch a nucleotide from inactive to active.The I182 region of k(ir)6.2 is closely associated with ligand binding in K(ATP) channel inhibition by ATPA cyclic nucleotide-gated channel mutation associated with canine daylight blindness provides insight into a role for the S2 segment tri-Asp motif in channel biogenesis.The structure of the prokaryotic cyclic nucleotide-modulated potassium channel MloK1 at 16 A resolution.Inner activation gate in S6 contributes to the state-dependent binding of cAMP in full-length HCN2 channel.Opening mechanism of a cyclic nucleotide-gated channel based on analysis of single channels locked in each liganded state.Mechanism of inhibition of cyclic nucleotide-gated channel by protein tyrosine kinase probed with genistein.Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP.Effects of ultraviolet modification on the gating energetics of cyclic nucleotide-gated channelsModification of cyclic nucleotide-gated ion channels by ultraviolet light.Mutation of a single residue in the S2-S3 loop of CNG channels alters the gating properties and sensitivity to inhibitorsA point mutation in the pore region alters gating, Ca(2+) blockage, and permeation of olfactory cyclic nucleotide-gated channelsIn vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors.Molecular regions controlling the activity of CNG channelsA cyclic nucleotide modulated prokaryotic K+ channel.Cyclic nucleotide-regulated cation channels.Coexpression of alpha and beta subunits of the rod cyclic GMP-gated channel restores native sensitivity to cyclic AMP: role of D604/N1201.A single intracellular cysteine residue is responsible for the activation of the olfactory cyclic nucleotide-gated channel by NO.Structure of a eukaryotic cyclic-nucleotide-gated channel.Ion channel structure and the promise of bacteria: cyclic nucleotide-gated channels in the queue.Role of the S4-S5 linker in CNG channel activation.Rotational movement during cyclic nucleotide-gated channel opening.CNGA3 is expressed in inner ear hair cells and binds to an intracellular C-terminus domain of EMILIN1.Voltage-dependent gating of hyperpolarization-activated, cyclic nucleotide-gated pacemaker channels: molecular coupling between the S4-S5 and C-linkers.Molecular mechanism of cAMP modulation of HCN pacemaker channels.
P2860
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P2860
Three amino acids in the C-linker are major determinants of gating in cyclic nucleotide-gated channels.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Three amino acids in the C-lin ...... lic nucleotide-gated channels.
@en
type
label
Three amino acids in the C-lin ...... lic nucleotide-gated channels.
@en
prefLabel
Three amino acids in the C-lin ...... lic nucleotide-gated channels.
@en
P2093
P2860
P356
P1433
P1476
Three amino acids in the C-lin ...... lic nucleotide-gated channels.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/17.2.353
P407
P577
1998-01-01T00:00:00Z