Molecular mechanisms controlling GLUT4 intracellular retention.
about
Rab4b is a small GTPase involved in the control of the glucose transporter GLUT4 localization in adipocyteA role for the CHC22 clathrin heavy-chain isoform in human glucose metabolismMyo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesiclesTUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recyclingInsulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesiclesGLUT4 is sorted to vesicles whose accumulation beneath and insertion into the plasma membrane are differentially regulated by insulin and selectively affected by insulin resistanceHigh basal cell surface levels of fish GLUT4 are related to reduced sensitivity of insulin-induced translocation toward GGA and AS160 inhibition in adipocytes.Insulin-regulated Glut4 translocation: membrane protein trafficking with six distinctive steps.The SLC2 (GLUT) family of membrane transporters.Identification of three distinct functional sites of insulin-mediated GLUT4 trafficking in adipocytes using quantitative single molecule imaging.Rab5 activity regulates GLUT4 sorting into insulin-responsive and non-insulin-responsive endosomal compartments: a potential mechanism for development of insulin resistanceMicroRNAs overexpressed in growth-restricted rat skeletal muscles regulate the glucose transport in cell culture targeting central TGF-β factor SMAD4Transport of deoxy-D-glucose into lymphocytes of patients with polycystic ovary syndrome.Single point mutations result in the miss-sorting of Glut4 to a novel membrane compartment associated with stress granule proteins.Critical roles for the COOH terminus of the Cu-ATPase ATP7B in protein stability, trans-Golgi network retention, copper sensing, and retrograde trafficking.GLUT4 exocytosis.The first luminal loop confers insulin responsiveness to glucose transporter 4.Insulin controls the spatial distribution of GLUT4 on the cell surface through regulation of its postfusion dispersal.Doc2b promotes GLUT4 exocytosis by activating the SNARE-mediated fusion reaction in a calcium- and membrane bending-dependent mannerSynip arrests soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE)-dependent membrane fusion as a selective target membrane SNARE-binding inhibitor.Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs.Inhibition of contraction-stimulated AMP-activated protein kinase inhibits contraction-stimulated increases in PAS-TBC1D1 and glucose transport without altering PAS-AS160 in rat skeletal muscle.SNARE proteins underpin insulin-regulated GLUT4 traffic.The sugar is sIRVed: sorting Glut4 and its fellow travelers.A proteolytic pathway that controls glucose uptake in fat and muscle.Camelus dromedarius glucose transporter 4: in silico analysis, cloning, expression, purification and characterisation in E. coli.Dynamic GLUT4 sorting through a syntaxin-6 compartment in muscle cells is derailed by insulin resistance-causing ceramide.Expression, purification, and functional characterization of the insulin-responsive facilitative glucose transporter GLUT4.The amino acid transporter, SLC1A3, is plasma membrane-localised in adipocytes and its activity is insensitive to insulin.Kinetics of GLUT4 trafficking in rat and human skeletal muscle.Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin.Molecular basis of insulin-responsive GLUT4 trafficking systems revealed by single molecule imaging.Characterization of GLUT4-containing vesicles in 3T3-L1 adipocytes by total internal reflection fluorescence microscopy.Downregulation of a GPCR by β-Arrestin2-Mediated Switch from an Endosomal to a TGN Recycling Pathway.
P2860
Q24312899-18C4F3FE-87E2-4835-8094-E133F9DBB9FEQ24314921-CEF48614-E137-453A-A470-969A38C78067Q28574848-A6231799-F83D-4B1F-9AE5-FF99C8892594Q29347249-D21A5A93-48CD-4D06-ABC8-F6578754C8B7Q30434989-B2D41056-C4B0-4CB9-9C8A-EF25746F9C1BQ30435746-13BAB593-9F66-424B-BA54-CBEA9E533C1BQ33655544-779D4AA3-DCC8-436D-8CDE-126D7CDAEFF7Q33792834-7CDC31C8-631A-4FEF-81F9-2C678B46D65AQ33926133-B7AA6F21-A92E-4054-8D7C-265536AEFD7FQ34029351-1ACA2E13-996F-4E65-8310-92EB6AB95E46Q34068389-C4CF104B-78E3-4FE7-B6AA-874D8D0D9F51Q34233643-55EBA140-27D9-41A9-8B0F-4AF8ED488D6FQ34375485-CD77A9BF-173F-4674-BFF9-65CFA40412F9Q34849061-31AA7A19-C463-406F-BBA8-62F638F49907Q35087086-F3113694-65F6-42A4-9A57-968D89854367Q35672106-3523472A-425F-4A2D-948D-3AD04DCF45A3Q35790922-C111AF46-B36A-40D1-8500-845CBA836055Q36189207-95676CA3-B269-4E30-B4FA-C7757C2BDF70Q36758428-4F39A3A9-C748-43F9-88DF-028E92B43F57Q36967305-861DF1CE-D141-42EA-B00C-09A9CFE3D8A4Q37098751-BA0BF690-0976-4649-A3C0-6BAF2C5A8447Q37163482-91BCFA24-1881-481E-8791-628B1FBE675EQ37827900-ACBAE8B2-8F0F-4963-A88A-069A84469034Q37838504-6567E49D-E5A5-4138-8224-529AC3EABE12Q38151511-E06EC4D2-A8EB-4B21-A44C-85964A58A629Q38821094-E48F9522-3F3B-44AA-A2E0-080B27988F69Q39623135-54B9AFF6-97B6-421D-83A9-F69EECBC09E2Q39719657-A99ED5FC-4402-4B1D-A839-1EE1243CA1BAQ41791641-A59F9F18-02A0-45B2-868D-210E2C475CB3Q41995118-BDCB2D44-09D7-4ED0-8902-DA8499E5DD1BQ42510738-1516CC6A-3648-4FD2-B60F-9C2C7ECFD97CQ42805723-D38E1292-4D34-409C-B441-3475C011CFDAQ42835189-BCB5AE84-E6FB-4262-9EB1-1FC0AA3B59D3Q51265394-209BE7C9-8D7D-4306-8BEA-B8C01E65A436
P2860
Molecular mechanisms controlling GLUT4 intracellular retention.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Molecular mechanisms controlling GLUT4 intracellular retention.
@en
type
label
Molecular mechanisms controlling GLUT4 intracellular retention.
@en
prefLabel
Molecular mechanisms controlling GLUT4 intracellular retention.
@en
P2860
P356
P1476
Molecular mechanisms controlling GLUT4 intracellular retention.
@en
P2093
Timothy E McGraw
Vincent Blot
P2860
P304
P356
10.1091/MBC.E08-03-0236
P577
2008-06-11T00:00:00Z