Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts.
about
Cellular replacement therapy for Parkinson's disease--where we are today?Neurotrophic factors and neural prostheses: potential clinical applications based upon findings in the auditory system.Delivery of sonic hedgehog or glial derived neurotrophic factor to dopamine-rich grafts in a rat model of Parkinson's disease using adenoviral vectors Increased yield of dopamine cells is dependent on embryonic donor ageAAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons.Response of aged parkinsonian monkeys to in vivo gene transfer of GDNFNogo-A Neutralization Improves Graft Function in a Rat Model of Parkinson's Disease.Effects of glial cell line-derived neurotrophic factor deletion on ventral mesencephalic organotypic tissue cultures.Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model.Enhancement of polysialic acid expression improves function of embryonic stem-derived dopamine neuron grafts in Parkinsonian mice.A perspective on bioactive cell microencapsulation.Striatal dopaminergic afferents concentrate in GDNF-positive patches during development and in developing intrastriatal striatal grafts.Cografting of carotid body cells improves the long-term survival, fiber outgrowth and functional effects of grafted dopaminergic neurons.Compacted DNA nanoparticle gene transfer of GDNF to the rat striatum enhances the survival of grafted fetal dopamine neurons.Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons.Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease.In vivo evaluation of pharmacologically active microcarriers releasing nerve growth factor and conveying PC12 cells.Olfactory ensheathing glial co-grafts improve functional recovery in rats with 6-OHDA lesions.Simultaneous Transplantation of Fetal Ventral Mesencephalic Tissue and Encapsulated Genetically Modified Cells Releasing GDNF in a Hemi-Parkinsonian Rat Model of Parkinson's Disease.Differential effects of Bcl-2 overexpression on fibre outgrowth and survival of embryonic dopaminergic neurons in intracerebral transplants.Combination of cell transplantation and glial cell line-derived neurotrophic factor-secreting encapsulated cells in Parkinson's disease
P2860
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P2860
Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Implants of polymer-encapsulat ...... of fetal dopaminergic grafts.
@en
type
label
Implants of polymer-encapsulat ...... of fetal dopaminergic grafts.
@en
prefLabel
Implants of polymer-encapsulat ...... of fetal dopaminergic grafts.
@en
P2093
P356
P1476
Implants of polymer-encapsulat ...... of fetal dopaminergic grafts.
@en
P2093
Aebischer P
Braguglia D
P304
P356
10.1006/EXNR.1997.6718
P407
P577
1998-01-01T00:00:00Z