X-gene product of hepatitis B virus induces apoptosis in liver cells.
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The enigmatic X gene of hepatitis B virusHepatitis Bx antigen stimulates expression of a novel cellular gene, URG4, that promotes hepatocellular growth and survivalHepatitis B virus, HBx mutants and their role in hepatocellular carcinomaAvian Reoviruses Cause Apoptosis in Cultured Cells: Viral Uncoating, but Not Viral Gene Expression, Is Required for Apoptosis InductionInhibition of apoptosis by oncogenic hepatitis B virus X protein: Implications for the treatment of hepatocellular carcinomaThe translation initiation factor, hu-Sui1 may be a target of hepatitis B X antigen in hepatocarcinogenesisHepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2Hepatitis B virus molecular biology and pathogenesisTranscriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue.Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potentialTransfection and expression of hepatitis B virus x gene and its effect on apoptosis in HL-7702 cells.Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic miceDifferent regions of hepatitis B virus X protein are required for enhancement of bZip-mediated transactivation versus transrepression.Role of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein.Hepatitis B virus biology.Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways.Direct association and nuclear import of the hepatitis B virus X protein with the NF-kappaB inhibitor IkappaBalphaParacrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: an alternative mechanism of HBx-related pathogenesisInteraction of Hepatitis B virus with cellular processes in liver carcinogenesis.Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x proteinGenetic mechanisms of hepatocarcinogenesis.Chronic hepatitis B infection and liver cancer.The roles of hepatitis B virus-encoded X protein in virus replication and the pathogenesis of chronic liver disease.Modulation of apoptotic signaling by the hepatitis B virus X protein.Structural and biochemical analysis of Bcl-2 interaction with the hepatitis B virus protein HBxHepatitis B virus X protein modulates apoptosis in human renal proximal tubular epithelial cells by activating the JAK2/STAT3 signaling pathway.c-Myc induction of programmed cell death may contribute to carcinogenesis: a perspective inspired by several concepts of chemical carcinogenesis.The molecular and pathophysiological implications of hepatitis B X antigen in chronic hepatitis B virus infection.Tackling hepatitis B virus-associated hepatocellular carcinoma--the future is now.Using proteomics to identify the HBx interactome in hepatitis B virus: how can this inform the clinic?HBx-dependent cell cycle deregulation involves interaction with cyclin E/A-cdk2 complex and destabilization of p27Kip1.HBx protein of hepatitis B virus activates Jak1-STAT signaling.Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal.Hepatitis B Virus X and Regulation of Viral Gene Expression.Hepatitis B Virus Core Promoter A1762T/G1764A (TA)/T1753A/T1768A Mutations Contribute to Hepatocarcinogenesis by Deregulating Skp2 and P53.Interaction of mutant hepatitis B X protein with p53 tumor suppressor protein affects both transcription and cell survival.DDB2 induces nuclear accumulation of the hepatitis B virus X protein independently of binding to DDB1.Hepatitis B virus X protein acts as a tumor promoter in development of diethylnitrosamine-induced preneoplastic lesions.The hepatitis B viral X protein activates NF-kappaB signaling pathway through the up-regulation of TBK1.Interference of Apoptosis by Hepatitis B Virus.
P2860
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P2860
X-gene product of hepatitis B virus induces apoptosis in liver cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
X-gene product of hepatitis B virus induces apoptosis in liver cells.
@en
type
label
X-gene product of hepatitis B virus induces apoptosis in liver cells.
@en
prefLabel
X-gene product of hepatitis B virus induces apoptosis in liver cells.
@en
P2093
P2860
P356
P1476
X-gene product of hepatitis B virus induces apoptosis in liver cells.
@en
P2093
P2860
P304
P356
10.1074/JBC.273.1.381
P407
P577
1998-01-01T00:00:00Z