Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade
about
RMP, a novel RNA polymerase II subunit 5-interacting protein, counteracts transactivation by hepatitis B virus X proteinThe enigmatic X gene of hepatitis B virusHepatitis B virus replication is associated with an HBx-dependent mitochondrion-regulated increase in cytosolic calcium levelsProteasome complex as a potential cellular target of hepatitis B virus X proteinHepatitis Bx antigen stimulates expression of a novel cellular gene, URG4, that promotes hepatocellular growth and survivalTargeted therapy for hepatocellular carcinoma: novel agents on the horizonHepatitis B virus, HBx mutants and their role in hepatocellular carcinomaHepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alphaStructural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complexThe translation initiation factor, hu-Sui1 may be a target of hepatitis B X antigen in hepatocarcinogenesisERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-kappaBOverexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liverHepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIHHepatitis B virus molecular biology and pathogenesisRole of hepatitis B virus X protein in regulating LIM and SH3 protein 1 (LASP-1) expression to mediate proliferation and migration of hepatoma cellsThe ORF3 protein of hepatitis E virus binds to Src homology 3 domains and activates MAPK.Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potentialLocalization of ERK/MAP kinase is regulated by the alphaherpesvirus tegument protein Us2Environmental factors as regulators and effectors of multistep carcinogenesis.Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex.Molecular genetics of hepatocellular neoplasia.SHP2 is induced by the HBx-NF-κB pathway and contributes to fibrosis during human early hepatocellular carcinoma development.Evaluation of transcriptional efficiency of hepatitis B virus covalently closed circular DNA by reverse transcription-PCR combined with the restriction enzyme digestion methodVirus associated malignancies: the role of viral hepatitis in hepatocellular carcinoma.Hepatitis B virus HBx protein deregulates cell cycle checkpoint controlsRegulation of RNA polymerase I-dependent promoters by the hepatitis B virus X protein via activated Ras and TATA-binding proteinHepatitis B virus X protein interferes with cellular DNA repair.Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic miceHepatitis B virus-induced oncogenesis.Different regions of hepatitis B virus X protein are required for enhancement of bZip-mediated transactivation versus transrepression.Hepatitis B virus X stimulates redox signaling through activation of ataxia telangiectasia mutated kinaseDuck hepatitis B virus expresses a regulatory HBx-like protein from a hidden open reading frameRole of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein.Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease.Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo.Hepatitis B virus biology.Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways.Direct association and nuclear import of the hepatitis B virus X protein with the NF-kappaB inhibitor IkappaBalphaTranscriptional regulation of the TATA-binding protein by Ras cellular signalingParacrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: an alternative mechanism of HBx-related pathogenesis
P2860
Q22008019-AE8566F9-097C-4DC9-9D11-A4CC70C51DAAQ24561887-013F78F1-AAF8-401A-90B5-F8001F24718AQ24681723-8B0F3EBB-6D6A-4D8F-8AED-2417687E7207Q24681896-7657AC40-0640-4F01-97E9-01165C898859Q24682883-D8D609E0-D6B2-4A47-9850-A0ED778D6422Q27002288-A0F0C90B-09EA-46B1-A364-BEE97CE3E933Q27024874-2FC95F0A-393C-446E-9F24-4A4A3D224516Q27485874-4D0E6C4E-FD4E-45EB-ABDE-47A593404D3AQ28140767-98728641-AAC0-45FA-B56A-2E74C9E1BF12Q28141874-81EF93A9-8E1C-47AA-90A7-FA0B2E33FEF9Q28144441-2B5C541B-7B02-4BEB-B2BC-81748951BA5DQ28246572-A6FAC62A-634B-4A1F-BE7A-E606271FCC14Q28573627-4260F31A-4AFC-4B6F-A921-1E72DAC46869Q28818406-F19EC8C7-D5F7-4C4E-BF86-C5C405E05817Q30010029-51EC7CF3-1E34-4EA5-9055-4997FE0F14ECQ30167985-0D66C183-1E41-4D1A-8988-A2CBFBE0942EQ30840853-427F7266-F932-4CC1-A02C-BB502F6AC669Q33248408-C7016F3A-6588-428D-AF53-3C4EA5E0F631Q33605331-C2429BFB-D205-48F7-938A-D0523A740517Q33649039-D7E9361D-FC2A-42DD-B353-6CCF9CF6500DQ33680701-1FFE74CF-EAB0-4BBD-9880-16A00167539CQ33689008-0EAF45F8-1963-44EB-9450-E9023EF6C92FQ33716406-C7539751-340D-408D-B999-7639FF4E7F81Q33723810-641AD405-95C9-4AE5-879F-7778DC0BC31EQ33765576-1AE04016-7BE1-42A0-A5C0-7970ED95F5D1Q33781677-63C4FCB5-C59C-4C10-9BC1-E701C4859781Q33781959-B89A2FFF-069E-4CAA-9F9B-A15015886C5EQ33787132-11AB995D-EC62-4EC6-9847-9EA32F46E575Q33787553-F40B9A39-D2D6-46EC-82DC-309702618310Q33794363-59CD8E61-48CD-4068-B521-EB17967AF2DCQ33802988-1393DD42-9E4F-4F96-A980-78C4535A94E2Q33834642-6E8316EE-77F0-463C-A675-6683988DCD4CQ33834716-5CBBCA01-80C3-4292-BBFD-141165AA0AA6Q33846198-0E2B9CB7-E17F-4360-B4BA-54B520FF390CQ33848045-0C50D3FA-3647-4D5F-A97C-B39C89CA1BCBQ33855246-E107FE21-A987-40E9-9CD3-CBE04A2BB0C9Q33926143-8416C849-BAD7-48BC-9B98-97A6EC293C9CQ33959538-E126BBAB-B91F-4ABA-8C6B-63C4C80D1AB6Q33964554-D1D7A5AF-DE8E-4F7A-BC0C-E906087D798CQ34068117-02B121FA-0743-4E7E-9FAF-4DFD135F5643
P2860
Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Hepatitis B virus HBx protein ...... , MAP kinase signaling cascade
@ast
Hepatitis B virus HBx protein ...... , MAP kinase signaling cascade
@en
type
label
Hepatitis B virus HBx protein ...... , MAP kinase signaling cascade
@ast
Hepatitis B virus HBx protein ...... , MAP kinase signaling cascade
@en
prefLabel
Hepatitis B virus HBx protein ...... , MAP kinase signaling cascade
@ast
Hepatitis B virus HBx protein ...... , MAP kinase signaling cascade
@en
P2860
P356
P1476
Hepatitis B virus HBx protein ...... , MAP kinase signaling cascade
@en
P2093
P2860
P304
10350-10354
P356
10.1073/PNAS.91.22.10350
P407
P577
1994-10-01T00:00:00Z