RTX toxins recognize a beta2 integrin on the surface of human target cells.
about
Virulence factor rtx in Legionella pneumophila, evidence suggesting it is a modular multifunctional proteinRTX proteins: a highly diverse family secreted by a common mechanismThe adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18)The CD11a partner in Sus scrofa lymphocyte function-associated antigen-1 (LFA-1): mRNA cloning, structure analysis and comparison with mammalian homologues.Identification of a vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage.LL-37 opsonizes and inhibits biofilm formation of Aggregatibacter actinomycetemcomitans at subbactericidal concentrations.Molecular and virulence characteristics of an outer membrane-associated RTX exoprotein in Pasteurella pneumotropicaInteraction of Actinobacillus actinomycetemcomitans outer membrane vesicles with HL60 cells does not require leukotoxin.Cholesterol-rich membrane microdomains mediate cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal-distending toxinThe wild boar (Sus scrofa) lymphocyte function-associated antigen-1 (CD11a/CD18) receptor: cDNA sequencing, structure analysis and comparison with homologuesProbing of Actinobacillus pleuropneumoniae ApxIIIA toxin-dependent cytotoxicity towards mammalian peripheral blood mononucleated cellsCytotoxic necrotizing factor from Escherichia coli induces RhoA-dependent expression of the cyclooxygenase-2 Gene.Abundant secretion of bioactive interleukin-1beta by human macrophages induced by Actinobacillus actinomycetemcomitans leukotoxinRecombinant bovine interleukin-1beta amplifies the effects of partially purified Pasteurella haemolytica leukotoxin on bovine neutrophils in a beta(2)-integrin-dependent manner.Inactivation of Pasteurella (Mannheimia) haemolytica leukotoxin causes partial attenuation of virulence in a calf challenge model.Influence of beta(2)-integrin adhesion molecule expression and pulmonary infection with Pasteurella haemolytica on cytokine gene expression in cattle.The role of the cell-mediated immune response to Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in periodontitis.Actinobacillus actinomycetemcomitans leukotoxin induces apoptosis in HL-60 cellsAnti-leukemia activity of a bacterial toxin with natural specificity for LFA-1 on white blood cells.Bacterial RTX toxins allow acute ATP release from human erythrocytes directly through the toxin pore.Cell adhesion molecules in the pathogenesis of and host defence against microbial infection.Cloning and characterization of two bistructural S-layer-RTX proteins from Campylobacter rectus.Correlation of Pasteurella haemolytica leukotoxin binding with susceptibility to intoxication of lymphoid cells from various species.Lymphocyte function-associated antigen 1 is a receptor for Pasteurella haemolytica leukotoxin in bovine leukocytes.Legionella pneumophila entry gene rtxA is involved in virulence.Mannheimia haemolytica leukotoxin activates a nonreceptor tyrosine kinase signaling cascade in bovine leukocytes, which induces biological effects.Intra- and interspecies regulation of gene expression by Actinobacillus actinomycetemcomitans LuxS.Blockade of the PI-3K signalling pathway by the Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces macrophages to synthesize and secrete pro-inflammatory cytokinesInflammatory cytokines enhance the interaction of Mannheimia haemolytica leukotoxin with bovine peripheral blood neutrophils in vitroBovine CD18 is necessary and sufficient to mediate Mannheimia (Pasteurella) haemolytica leukotoxin-induced cytolysisInteractions of extracts from selected chewing stick sources with Aggregatibacter actinomycetemcomitansFusobacterium nucleatum outer membrane proteins Fap2 and RadD induce cell death in human lymphocytesMembrane restructuring by Bordetella pertussis adenylate cyclase toxin, a member of the RTX toxin family.Pathogenic trickery: deception of host cell processes.Aggregatibacter actinomycetemcomitans leukotoxin (LtxA; Leukothera) induces cofilin dephosphorylation and actin depolymerization during killing of malignant monocytes.luxS and arcB control aerobic growth of Actinobacillus actinomycetemcomitans under iron limitation.Mechanisms underlying Actinobacillus pleuropneumoniae exotoxin ApxI induced expression of IL-1β, IL-8 and TNF-α in porcine alveolar macrophagesMonoclonal antibodies against Vibrio vulnificus RtxA1 elicit protective immunity through distinct mechanisms.Mannheimia haemolytica leukotoxin binds to lipid rafts in bovine lymphoblastoid cells and is internalized in a dynamin-2- and clathrin-dependent manner.Brief heat treatment increases cytotoxicity of Mannheimia haemolytica leukotoxin in an LFA-1 independent manner.
P2860
Q21263201-3960A5FE-927E-4B02-942B-C0AB6834E8D1Q24630254-8D5E5DEB-EB67-44D9-9FB0-D0B4CB47E244Q24675699-18B7BAF9-941E-4A08-B23B-1B318960E22EQ24812900-C85A127D-FBFF-4A93-BA11-2B79B38145B4Q30432626-317A48BA-6C32-40B6-97F4-239D2B28CA36Q30555350-62F1E8A4-0043-4DF4-8F61-C75449AE768EQ31003837-A45B7B0B-CD33-475F-A362-52C249176CC7Q31131373-D5DA9842-D615-46B8-8EA7-F853721AFBC0Q33239764-F3AB90FB-F374-4835-8B71-809219A8EA01Q33302692-2B77FA28-1ED9-4CBA-AD90-97DD272A019AQ33388553-EC5131FE-ACF4-4E7F-B92A-542716266F1AQ33552763-D97B286B-40D8-4A41-B49B-0C983CE9F3FEQ33557079-44461B80-86FC-4F91-ADE9-7E3A13339758Q33591399-12A90D3C-C611-4BBC-8CB7-3BA1F87527F4Q33596232-EC9CE886-BFB2-452A-AD89-4FACD03E26FCQ33598775-F4C6F87F-7507-4603-9B6A-A7060C682CB1Q33752057-DDD9FE14-AC18-45BB-A9D7-B260D6BAD840Q33763147-7936F957-127F-4953-8FFD-F49F39149CE8Q33808241-B4BD8E80-656A-4B94-B07F-A4AEE4126986Q33846524-2BD17326-F576-4441-9141-6EA66523B78BQ33850097-F8E95150-0A80-42CE-B0ED-41C29A7AEB81Q33991777-DA9951C3-332E-459B-837E-A8E1FF8454CBQ34002667-87588F61-947E-47AE-855B-B82B9C73622EQ34002954-1559BA46-0A8D-4A87-A1DD-8DC0497A6923Q34005732-90754AAB-982F-4A8A-8EE6-6F66B68100FCQ34009259-55A40010-0803-4BB1-9AD9-9C4BD0931E76Q34009791-F12D8A46-986E-4CEF-970B-8DCA7F3EF37DQ34097954-66B302B2-DEDA-4BC8-B11D-EF8FF130F3B6Q34129232-532A4224-C619-429C-BB0B-BACCF1F459AEQ34129944-7115A064-874A-4DEE-A971-02D21A23F702Q34248592-C450C655-B90D-4D26-87F2-8138155757C5Q34290736-6B000C19-A32C-4C7C-B334-168A90050601Q34324299-55D4140D-E658-4D58-A5E4-9FFB4E78AEF9Q34325331-C89B2599-528A-44FA-AAB3-BF5C17EDB23FQ34447303-B2D27863-6CEC-4D84-AA15-6DD035EA517FQ34523264-2DF062E9-C4C6-40BF-AE62-BB3924B7A88EQ34585637-931CD282-738A-4C7C-A875-CCF508E5943EQ34596138-FCB66769-AFF5-47ED-829F-371674257D30Q34660304-88968696-C85C-47E1-A7C6-0164DD27D0F9Q34934609-618332D9-514A-4D88-8E8E-AE6AF1B081EA
P2860
RTX toxins recognize a beta2 integrin on the surface of human target cells.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
RTX toxins recognize a beta2 integrin on the surface of human target cells.
@en
type
label
RTX toxins recognize a beta2 integrin on the surface of human target cells.
@en
prefLabel
RTX toxins recognize a beta2 integrin on the surface of human target cells.
@en
P2093
P2860
P356
P1476
RTX toxins recognize a beta2 integrin on the surface of human target cells.
@en
P2093
Billings PC
Korostoff J
Robinson MK
Rosenbloom J
Shenker BJ
P2860
P304
30463-30469
P356
10.1074/JBC.272.48.30463
P407
P577
1997-11-01T00:00:00Z